Dr Toby Trahair, Conjoint Lecturer with the School of Women's & Children's Health, and Paediatric Haematologist and Oncologist from the Kids Cancer Centre leads the current research in the area of haematology oncology.
The current research project is titled "Predictive clinical and genetic factors for the side-effects of chemotherapy in children treated for acute lymphoblastic leukemia" (ALL).
- to develop methods to identify acute lymphoblastic leukaemia patients at high risk of severe toxicity
- to measure quality of life and economic impact of severe-toxicities
- to develop interventions to reduce the incidence and impact of severe treatment-related toxicities
The study has two ongoing components:
- The ERASE cohort: a retrospective analysis of treatment-related toxicities in a cohort of >1000 Australian ALL patients (Evaluation of the Risk of Acute Lymphoblastic Leukaemia Treatment Side-Effects)
- The ASSET study: an Australian and New Zealand prospective acute lymphoblastic leukaemia bio-registry (Acute Lymphoblastic Leukaemia Subtype and Side-Effects from Treatment) study
The ASSET study is being run in conjunction with the Kids Cancer Alliance and Australian and Children’s Haematology and Oncology Group and Children’s Cancer Centres across Australia and New Zealand. Cross-disciplinary collaborators in the project include leukaemia biology, genomics, behavioural sciences and health economics.