Dr Duohui Jing

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Contact Category:

Conjoint

Discipline:

Paediatrics

Dr Duohui Jing graduated from Tsinghua University, China in 2004, and undertook doctoral study on Internal Medicine at Technische Universität Dresden, Germany. In 2011, he relocated from Germany to Australia and started his post-doctoral research on molecular mechanisms of chemo-resistance in acute lymphoblastic leukaemia (ALL). Dr Jing has published 8 first/corresponding-author papers, including Cancer Cell 2018 (first- and co-corresponding-author; Cover Story of the December issue 2018; IF = 27.4), Blood 2015 (first-author, IF = 15.1), Haematologica 2010 & 2012 (first-author, IF = 9.1). His publications have received >770 citations (Google Scholar) at an average of 51/article. In 2016, Dr Jing was awarded a Cancer Institute NSW Early Career Fellowship. Over the past four years, Dr Jing, as Chief Investigator A, has been awarded 4 grants of a total $990,000. Currently Dr Jing is employed as a Senior Research Officer in Children's Cancer Institute and conjoint Senior Lecturer, UNSW, Australia.

School:

Sch Women's&Children's Health

Email:

DJing@ccia.unsw.edu.au

University role:

Senior Research Officer

Qualifications:

Year Awarded	Degree	Speciality	University	Country
08.2004	Bachelor of Science	Biological Science	Tsinghua University	China
08.2006	Master of Science	Molecular Bioengineering	Dresden University of Technology	Germany
08.2010	Doctor rerum Medicinalium (German, equal to PhD)	Internal Medicine (Haematology)	Dresden University of Technology	Germany

Awards:

2019 UNSW publication award (Promoting High Quality Research Papers Scheme – Key Incentive 1), UNSW, Australia

2018 Nomination (Finalist of 20) of 2018 Golden Wattle Awards (Outstanding Australian Chinese Youth)

2018 Research Excellence Award, Australian Association for Chinese Biomedical Scientists, October 2018

2017 Service Excellence Award, Australian Association for Chinese Biomedical Scientists, November 2017

2016 Balnaves Foundation and Children’s Cancer Institute Travel Grant

2016 Roche New Investigator Travel Grant, at the New Directions in Leukaemia Research Conference, Noosa, March 2016

2015 Illumina Early Career Researcher Speaker Awards – second place, at Epigenetics Conference, Hobart, November 2015

Research

Field of Research (FOR) Tag:

Paediatrics

Cancer Cell Biology

Haematological Tumours

Haematology

Teaching & Supervision

I am available to supervise:

Yes

Areas of supervision:

Project Topics for current Honours and PhD Students:

Epigenetic mechanisms in clonal selection of paediatric acute lymphoblastic leukaemia through glucocorticoid-based therapeutics
Reversing glucocorticoid resistance in paediatric acute lymphoblastic leukaemia - a novel epigenetic mechanism linked to basic DNA structure

Media

Facebook:

https://www.facebook.com/UNSWWomensChildrensHealth/

LinkedIn:

http://au.linkedin.com/in/duohuijing

Publications related to this Person

Journal articles

Jamieson SMF; Gu Y; Guise CP; Foehrenbacher A; Pullen SM; Smaill JB; Patterson AV; Wilson WR; Manesh DM; El-Hoss J, 2014, 'A novel fluorometric assay for aldo-keto reductase 1C3 predicts metabolic activation of the nitrogen mustard prodrug PR-104A in human leukaemia cells', Biochemical Pharmacology, http://dx.doi.org/10.1016/j.bcp.2013.12.019

Jing D; Wobus M; Poitz DM; Bornhäuser M; Ehninger G; Ordemann R, 2012, 'Oxygen tension plays a critical role in the hematopoietic microenvironment in vitro', Haematologica, vol. 97, pp. 331 - 339, http://dx.doi.org/10.3324/haematol.2011.050815

Jing D; Fonseca AV; Alakel N; Fierro FA; Muller K; Bornhauser M; Ehninger G; Corbeil D; Ordemann R, 2010, 'Hematopoietic stem cells in co-culture with mesenchymal stromal cells -modeling the niche compartments in vitro', Haematologica, vol. 95, pp. 542 - 550, http://dx.doi.org/10.3324/haematol.2009.010736

Jing D; Oelschlaegel U; Ordemann R; Hölig K; Ehninger G; Reichmann H; Ziemssen T; Bornhäuser M, 2010, 'CD49d blockade by natalizumab in patients with multiple sclerosis affects steady-state hematopoiesis and mobilizes progenitors with a distinct phenotype and function', Bone Marrow Transplantation, vol. 45, pp. 1489 - 1496, http://dx.doi.org/10.1038/bmt.2009.381

Jing D; Alakel N; Bornhäuser M; Ehninger G; Ordemann R, 2010, 'SDF-1/CXCR4 blockade to mobilize hematopoietic progenitor cells from the placenta', Bone Marrow Transplantation, vol. 45, pp. 1661 - 1662, http://dx.doi.org/10.1038/bmt.2010.22

Seib FP; Franke M; Jing D; Werner C; Bornhäuser M, 2009, 'Endogenous bone morphogenetic proteins in human bone marrow-derived multipotent mesenchymal stromal cells', European Journal of Cell Biology, vol. 88, pp. 257 - 271, http://dx.doi.org/10.1016/j.ejcb.2009.01.003

Alakel N; Jing D; Muller K; Bornhauser M; Ehninger G; Ordemann R, 2009, 'Direct contact with mesenchymal stromal cells affects migratory behavior and gene expression profile of CD133⁺ hematopoietic stem cells during ex vivo expansion', Experimental Hematology, vol. 37, pp. 504 - 513, http://dx.doi.org/10.1016/j.exphem.2008.12.005

Fierro F; Illmer T; Jing D; Schleyer E; Ehninger G; Boxberger S; Bornhäuser M, 2007, 'Inhibition of platelet-derived growth factor receptorβ by imatinib mesylate suppresses proliferation and alters differentiation of human mesenchymal stem cells in vitro', Cell Proliferation, vol. 40, pp. 355 - 366, http://dx.doi.org/10.1111/j.1365-2184.2007.00438.x

Cao W; Wang A; Jing D; Gong Y; Zhao N; Zhang X, 2005, 'Novel biodegradable films and scaffolds of chitosan blended with poly(3-hydroxybutyrate)', Journal of Biomaterials Science, Polymer Edition, vol. 16, pp. 1379 - 1394, http://dx.doi.org/10.1163/156856205774472308

Cao W; Jing D; Li J; Gong Y; Zhao N; Zhang X, 2005, 'Effects of the degree of deacetylation on the physicochemical properties and Schwann cell affinity of chitosan films', Journal of Biomaterials Applications, vol. 20, pp. 157 - 177, http://dx.doi.org/10.1177/0885328205049897

Conference Papers

Jing D; Huang Y; Liu X; Sia K; Poulos RC; Span M; Zhang C; Mi J; Wong JWH; Beck D, 2018, 'Lymphocyte-specific chromatin accessibility predetermines glucocorticoid resistance in acute lymphoblastic leukemia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Chicago, IL, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago, IL, 14 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-3173

Other

Horton T, 2015, Yin and yang of glucocorticoid receptors in apoptosis, American Society of Hematology, http://dx.doi.org/10.1182/blood-2014-11-609206

School of Women's and Children's Health

Dr Duohui Jing

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