Dr Sean Kennedy

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Contact Category:

Academic

Discipline:

Paediatrics

Sean is the Director of Education in the School of Women's &Children's Health and Head of Paediatric Nephrology at Sydney Children's Hospital. His PhD was awarded in 2010 for the basic research thesis on The Role of Tissue Factor Cytoplasmic Domain & Protease Activated Receptors in Renal Ischaemia Perfusion Injury.

He is an active clinician, researcher and educator. He has been a member of the Scientific Programme & Education Committee of the Australian & New Zealand Society of Nephrology and was the Manager of the Paediatric Working Group of the Australian & New Zealand Dialysis and Transplant Registry (ANZDATA) between 20011 and 2017.

Sean is a medical advisor to Tuberous Sclerosis Australia and is recognised for his expertise in management of the renal manifestations of tuberous sclerosis complex (TSC). He has an ongoing research programme with his colleagues at the Sydney Children's Hospital TSC Clinic.

School:

Sch of Paediatrics

Phone:

(02) 9382 4834

Email:

sean.kennedy@unsw.edu.au

University role:

Senior Lecturer

Qualifications:

MBBS, FRACP, PhD

Keywords:

adolescence

chronic renal disease

hypertension

reperfusion injury

tuberous sclerosis

kidney transplantation

acute kidney injury

Research

Research activities:

My primary research activity is focussed on clinical studies aimed at improving outcomes for children with kidney disease. These research and clinical interests span the whole paediatric age group from the newborn period to adolescence and include children with congenital structural anomalies, those with end stage kidney disease who have had transplants or are on dialysis, as well as those with acute kidney injury.

Research in tuberous sclerosis includes studies exploring the molecular basis and clinical progression of benign tumours as well as research aimed at gaining a greater understanding of the needs of patients and their families.

Socio-economic Objective (SEO) tags:

Child Health

Clinical Health (Organs, Diseases and Abnormal Conditions)

Field of Research (FOR) Tag:

Paediatrics

Nephrology and Urology

Innate Immunity

Teaching & Supervision

I am available to supervise:

Yes

Areas of supervision:

Higher degree by research in paediatrics, paediatric nephrology, nephrology

BSc Honours and Independent Learning Projects

Currently supervising:

Masters by research

Glomerular Hyperfiltration and risk of Acute Kidney Injury
Neuroradiological features of Tuberous Sclerosis Complex as Biomarkers of Neurological Outcome

Media

Facebook:

https://www.facebook.com/UNSWPaediatrics

Publications related to this Person

Book Chapters

Rosenberg A; kennedy S, 2012, 'Urinary Tract Infections', in Textbook of Clinical Pediatrics, Springer

Womersley RA, 1967, 'Urinary tract infections.', in Postgraduate Medical Journal

Journal articles

MacIntyre CR; Shaw P; Mackie FE; Boros C; Marshall H; Barnes M; Seale H; Kennedy SE; Moa A; Hayen A, 2016, 'Immunogenicity and persistence of immunity of a quadrivalent Human Papillomavirus (HPV) vaccine in immunocompromised children', Vaccine, vol. 34, pp. 4343 - 4350, http://dx.doi.org/10.1016/j.vaccine.2016.06.049

Marokakis S; Kasparian NA; Kennedy SE, 2016, 'Prenatal counselling for congenital anomalies: a systematic review', Prenatal Diagnosis, vol. 36, pp. 662 - 671, http://dx.doi.org/10.1002/pd.4836

Cohn SL; Gautam B; Preddy JS; Connors JR; Kennedy SE, 2016, 'Barriers to the use of paediatric clinical practice guidelines in rural and regional New South Wales Australia', Australian Journal of Rural Health, vol. 24, pp. 23 - 28, http://dx.doi.org/10.1111/ajr.12190

Wyld ML; Clayton PA; Kennedy SE; Alexander SI; Chadban SJ, 2015, 'Pregnancy outcomes for kidney transplant recipients with transplantation as a child', JAMA Pediatrics, vol. 169, pp. e143626, http://dx.doi.org/10.1001/jamapediatrics.2014.3626

Le Page AK; Johnstone LM; Kennedy SE, 2015, 'Australian deceased donor kidney allocation protocols: Transplant waiting and graft quality for children and adolescents', Pediatric Transplantation, http://dx.doi.org/10.1111/petr.12544

Didsbury MS; Mackie FE; Kennedy SE, 2015, 'A systematic review of acute kidney injury in pediatric allogeneic hematopoietic stem cell recipients', Pediatric Transplantation, vol. 19, pp. 460 - 470, http://dx.doi.org/10.1111/petr.12483

Adam A; Myint M; Kennedy SE; Dally E; Challis D, 2015, 'Congenital Anterior Urethral Diverticulum: Antenatal Diagnosis with Subsequent Neonatal Endoscopic Management', Urology, vol. 85, pp. 914 - 917, http://dx.doi.org/10.1016/j.urology.2014.12.015

Cohn SL; Gautam B; Preddy JS; Connors JR; Kennedy SE, 2015, 'Barriers to the use of paediatric clinical practice guidelines in rural and regional New South Wales Australia', Australian Journal of Rural Health, http://dx.doi.org/10.1111/ajr.12190

McTaggart S; Danchin M; Ditchfield M; Hewitt I; Kausman J; Kennedy S; Trnka P; Williams G, 2015, 'KHA-CARI guideline: Diagnosis and treatment of urinary tract infection in children', Nephrology, vol. 20, pp. 55 - 60, http://dx.doi.org/10.1111/nep.12349

Thakkar D; Deshpande AV; Kennedy SE, 2014, 'Epidemiology and demography of recently diagnosed cases of posterior urethral valves', Pediatric Research, vol. 76, pp. 560 - 563, http://dx.doi.org/10.1038/pr.2014.134

Grace BS; Kara T; Kennedy SE; Mcdonald SP, 2014, 'Racial disparities in pediatric kidney transplantation in New Zealand', Pediatric Transplantation, http://dx.doi.org/10.1111/petr.12322

Cardamone M; Flanagan D; Mowat D; Kennedy SE; Chopra M; Lawson JA, 2014, 'Mammalian target of rapamycin inhibitors for intractable epilepsy and subependymal giant cell astrocytomas in tuberous sclerosis complex', Journal of Pediatrics, vol. 164, pp. 1195 - 1200, http://dx.doi.org/10.1016/j.jpeds.2013.12.053

Grace BS; Kennedy SE; Clayton PA; McDonald SP, 2014, 'Racial disparities in paediatric kidney transplantation', Pediatric Nephrology, vol. 29, pp. 125 - 132, http://dx.doi.org/10.1007/s00467-013-2572-y

van Stralen KJ; Jager KJ; Borzych-Duzalka D; Schaefer F; Hataya H; Kennedy SE; Verrina E; Inward C; Rönnholm K; Vondrak K, 2014, 'Survival and clinical outcomes of children starting renal replacement therapy in the neonatal period', Kidney International, http://dx.doi.org/10.1038/ki.2013.561

Zhang LF; Ho JSW; Kennedy SE, 2014, 'A systematic review of the psychometric properties of transition readiness assessment tools in adolescents with chronic disease', BMC Pediatrics, vol. 14, http://dx.doi.org/10.1186/1471-2431-14-4

Le Page AK; Mackie FE; McTaggart SJ; Kennedy SE, 2013, 'Cytomegalovirus & Epstein Barr Virus serostatus as a predictor of the long-term outcome of kidney transplantation', Nephrology, vol. 18, pp. 813 - 819, http://dx.doi.org/10.1111/nep.12149

Bates MJ; Ziegler JB; Kennedy SE; Mindel A; Wodak AD; Zoloth LS; Tobian AAR; Morris BJ, 2013, 'Recommendation by a law body to ban infant male circumcision has serious worldwide implications for pediatric practice and human rights', BMC Pediatrics, vol. 13, http://dx.doi.org/10.1186/1471-2431-13-136

Kennedy SE; Bailey R; Kainer G, 2012, 'Causes and outcome of late referral of children who develop end-stage kidney disease', Journal of Paediatrics and Child Health, vol. 48, pp. 253 - 258, http://dx.doi.org/10.1111/j.1440-1754.2011.02254.x

Ip EC; Kirby RE; Craig E; Mackie FE; Kennedy SE; Rosenberg AR; Kainer G; Frawley JE; Haghighi KS, 2012, 'Safety and adequacy of percutaneous biopsies in pediatric orthotopic kidney transplantation', International Journal of Organ Transplantation Medicine, vol. 3, pp. 26 - 29

Seale H; Trung L; Mackie FE; Kennedy SE; Boros C; Marshall H; Tidswell J; Shaw PJ; Montgomery K; MacIntyre CR, 2012, 'A qualitative study investigating knowledge and attitudes regarding human papillomavirus (HPV) and the HPV vaccine among parents of immunosuppressed children', Vaccine, vol. 30, pp. 7027 - 7031, http://dx.doi.org/10.1016/j.vaccine.2012.09.066

Ritchie AG; Clayton PA; MacKie FE; Kennedy SE, 2012, 'Nationwide survey of adolescents and young adults with end-stage kidney disease', Nephrology, vol. 17, pp. 539 - 544, http://dx.doi.org/10.1111/j.1440-1797.2012.01610.x

Rao J; Kennedy SE; Cohen S; Rosenberg AR, 2012, 'A systematic review of interventions for reducing pain and distress in children undergoing voiding cystourethrography', Acta Paediatrica, International Journal of Paediatrics, vol. 101, pp. 224 - 229, http://dx.doi.org/10.1111/j.1651-2227.2011.02482.x

Chopra M; Lawson JA; Wilson M; Kennedy SE; Taylor P; Buckley MF; Wargon O; Parasivam G; Camphausen C; Yates D, 2011, 'An Australian tuberous sclerosis cohort: Are surveillance guidelines being met?', Journal of Paediatrics and Child Health, vol. 47, pp. 711 - 716, http://dx.doi.org/10.1111/j.1440-1754.2011.02038.x

Bordador EB; Johnson DW; Henning P; Kennedy SE; McDonald SP; Burke JR; McTaggart SJ, 2010, 'Epidemiology and outcomes of peritonitis in children on peritoneal dialysis in Australasia', Pediatric Nephrology, vol. 25, pp. 1739 - 1745, http://dx.doi.org/10.1007/s00467-010-1510-5

Delaney D; Kennedy SE; Tobias VH; Farnsworth RH, 2009, 'Congenital unilateral renal tubular dysgenesis and severe neonatal hypertension', Pediatric Nephrology, vol. 24, pp. 863 - 867, http://dx.doi.org/10.1007/s00467-008-1035-3

Kennedy S, 2009, 'UTI in children - Part 1', Australian Doctor, pp. 25 - 30

Kennedy S, 2009, 'How to Treat UTI In children - Part 2', Australian Doctor, pp. 23 - 24

Kennedy SE; Erlich JH, 2008, 'Murine renal ischaemia-reperfusion injury', Nephrology, vol. 13, pp. 390 - 396, http://dx.doi.org/10.1111/j.1440-1797.2008.00979.x

Watterson LM; Hyde S; Bajenov S; Kennedy SE, 2007, 'The training environment of junior anaesthetic registrars learning epidural labour analgesia in Australian teaching hospitals', Anaesthesia and Intensive Care, vol. 35, pp. 38 - 45

Sevastos J; Kennedy SE; Davis DR; Sam M; Peake PW; Charlesworth JA; Mackman N; Erlich JH, 2007, 'Tissue factor deficiency and PAR-1 deficiency are protective against renal ischemia reperfusion injury', Blood, vol. 109, pp. 577 - 583, http://dx.doi.org/10.1182/blood-2006-03-008870

Davis DR; Wilson K; Sam MJ; Kennedy SE; Mackman N; Charlesworth JA; Erlich JH, 2007, 'The development of cardiac fibrosis in low tissue factor mice is gender-dependent and is associated with differential regulation of urokinase plasminogen activator', Journal of Molecular and Cellular Cardiology, vol. 42, pp. 559 - 571, http://dx.doi.org/10.1016/j.yjmcc.2006.11.017

Kennedy SE; Shrikanth S; Charlesworth JA, 2006, 'Acute granulomatous tubulointerstitial nephritis caused by intravesical BCG', Nephrology Dialysis Transplantation, vol. 21, pp. 1427 - 1429, http://dx.doi.org/10.1093/ndt/gfk071

Kennedy SE; Mackie FE; Craig E; Kainer G, 2006, 'The choice of threshold limits for pediatric ambulatory blood pressure monitoring influences clinical decisions', Blood Pressure Monitoring, vol. 11, pp. 119 - 123, http://dx.doi.org/10.1097/01.mbp.0000209085.55364.73

Kennedy SE; Mackie FE; Rosenberg AR; McDonald SP, 2006, 'Waiting time and outcome of kidney transplantation in adolescents', Transplantation, vol. 82, pp. 1046 - 1050, http://dx.doi.org/10.1097/01.tp.0000236030.00461.f4

Kennedy SE; Shen Y; Charlesworth JA; Mackie JD; Mahony JD; Kelly JJP; Pussell BA, 2005, 'Outcome of overseas commercial kidney transplantation: An Australian perspective', Medical Journal of Australia, vol. 182, pp. 224 - 227

Verran DJ; Kennedy SE; Shen Y; Charlesworth JA; Mackie JD; Mahony JD; Kelly JJP; Pussell BA, 2005, 'Outcome of overseas commercial kidney transplantation: An Australian perspective (multiple letters) [5]', Medical Journal of Australia, vol. 183, pp. 54

Kennedy SE; Mackie FE; Rosenberg AR; Craig E; Kainer G, 2005, 'Agreement on reporting of ambulatory blood pressure monitoring in children', Pediatric Nephrology, vol. 20, pp. 1766 - 1768, http://dx.doi.org/10.1007/s00467-005-2066-7

Kennedy SE; Henry RL; Rosenberg AR, 2005, 'Antibiotic-related renal failure and cystic fibrosis', Journal of Paediatrics and Child Health, vol. 41, pp. 382 - 383, http://dx.doi.org/10.1111/j.1440-1754.2005.00640.x

Connor FL; Rosenberg AR; Kennedy SE; Bohane TD, 2003, 'HBV associated nephrotic syndrome: Resolution with oral lamivudine', Archives of Disease in Childhood, vol. 88, pp. 446 - 449, http://dx.doi.org/10.1136/adc.88.5.446

Conference Papers

Kennedy SE; Mackie F; Kainer G; Craig E; Rosenberg A, 2009, 'OUTCOMES OF PAEDIATRIC KIDNEY TRANSPLANTS AFTER CONVERSION TO SIROLIMUS', in Pediatric Nephrology, Springer, New York, NY, USA, pp. 646 - 646, 01 January 2009

Reports

Conference Presentations

Davis D; Wilson K; Sam M; Kennedy S; Mackman N; Erlich J, 2006, 'Gender modulates the effects of tissue factor deficiency on myocardial matrix remodelling and urokinase plasminogen activator expression', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Chicago, IL, Vol. 114, pp. 29 - 29, presented at 79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, 12 - 15 November 2006, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000241792800152&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Abstracts

Kennedy SE; Cameron, B; Mackie, FE, 2015, 'The efficacy of valganciclovir for prevention of infections with CMV and EBV after kidney transplant in children', in Pediatric Transplantation, Wiley: 12 months, presented at IPTA 8th Congress on Pediatric Transplantation

Krischock L; Kennedy S; Hayen A, 2015, 'CHARACTERISTICS AND OUTCOMES OF DIALYSIS IN AUSTRALIAN ADOLESCENTS AND YOUNG ADULTS', in NEPHROLOGY DIALYSIS TRANSPLANTATION, OXFORD UNIV PRESS, London, ENGLAND, Vol. 30, presented at 52nd Congress of the European-Renal-Association-European-Dialysis-and-Transplant-Assocation, London, ENGLAND, 28 - 31 May 2015, http://dx.doi.org/10.1093/ndt/gfv183.38

School of Women's and Children's Health

Dr Sean Kennedy

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