Professor William Ledger

Tabs

Main

Contact Category:

Academic

Discipline:

Obstetrics & Gynaecology

Qualifications: MA, DPhil (Oxon), MB, ChB, FRCOG, FRANZCOG, CREI

Professor William Ledger is the Head and Professor of the Discipline of Obstetrics & Gynaecology in the School of Women's & Children's Health. He is a senior fertility specialist, obstetrician and gynaecologist and was the Chair and Head of the Academic Unit for Reproductive and Developmental Medicine at the University of Sheffield, UK until 2011.

Research Interests: I am interested in all aspects of reproductive medicine and surgery. Research projects range from clinical studies to improve safety and efficacy of IVF to molecular biology of the implanting embryo. The over-arching theme of this aspect of our work is to assess the developmental impact of conception "in vitro" in comparison with natural conception. We study ectopic pregnancies obtained after salpingectomy, embryonic tissue and samples collected at delivery from cord blood and placenta. Collaborative studies include work on cost effectiveness and health economics of assisted conception, implantation and embryonic genomic activation as a model of carcinogenesis, fertility preservation for young patients with cancer, and management of recurrent implantation failure.

ILP Research Interests (Will supervise ILP students): Reproduction

Project Topics for current Honours Students: MicroRNAs in pregnancy and parturition

Teaching Interests: We actively participate in all three phases of the undergraduate curriculum of the UNSW Medical School. I also supervise Honours and ILP students and postgraduates sitting Membership and CREI examinations.

Society Memberships & Professional Activities: Member of British Fertility Society, American Society for Reproductive Medicine, European Society for Human Reproduction and Embryology, Royal College of Obstetricians and Gynaecologists, Royal Australian College of Obstetricians and Gynaecologists, Medical Defence Union, Gynaecological Visiting Society,

Professional Activities:

Chair – Miscarriage Misdiagnosis Clinical Review Team. Irish Health Service Executive 2010 –
Member, Editorial Board, Clinical Endocrinology 2004 -
Member - Editorial Board, Current Obstetrics and Gynaecology 2001 –
Member – Editorial Board, British Journal of Obstetrics and Gynaecology 2003 –
Member – Editorial Board, Women’s Health 2006 -
Member – Editorial Board, Reproductive Biomedicine Online 2008 -
Member – Pituitary Foundation Clinical Advisory Committee

Research Keywords:

Assisted reproduction, particularly ‘Mild’ IVF, and gynaecological disorders including endometriosis,polycystic ovary syndrome (PCOS) and premature menopause

School:

Discip Obstetrics&Gynaecology

Phone:

(02) 9382 6515

Email:

w.ledger@unsw.edu.au

University role:

Head of School and Head of Discipline of Obstetrics & Gynaecology

Research

Socio-economic Objective (SEO) tags:

Women's Health

Reproductive System and Disorders

Field of Research (FOR) Tag:

Obstetrics and Gynaecology

Fertility

Reproduction

Teaching & Supervision

Supervision keywords:

reproduction

Media

Facebook:

https://www.facebook.com/UNSWWomensChildrensHealth

Publications related to this Person

Books

Book Chapters

Journal articles

Wang Y; Logan S; Stern K; Wakefield CE; Cohn RJ; Agresta F; Jayasinghe Y; Deans R; Segelov E; McLachlan RI, 2019, 'Supportive oncofertility care, psychological health and reproductive concerns: a qualitative study', Supportive Care in Cancer, http://dx.doi.org/10.1007/s00520-019-04883-1

Anazodo A; Ledger W, 2019, 'Assessing and Supporting Adolescent Boys Having Fertility Preservation', In: Woodruff T., Shah D., Vitek W. (eds) Textbook of Oncofertility Research and Practice., pp. 507 - 512, http://dx.doi.org/10.1007/978-3-030-02868-8_53

Richani D; Constance K; Lien S; Agapiou D; Stocker WA; Hedger MP; Ledger WL; Thompson JG; Robertson DM; Mottershead DG, 2019, 'Cumulin and FSH cooperate to regulate inhibin B and activin B production by human granulosa-lutein cells in vitro', Endocrinology, vol. 160, pp. 853 - 862, http://dx.doi.org/10.1210/en.2018-01026

Weddell S; Jones GL; Duffy S; Hogg C; Johnson S; Ledger W, 2019, 'Home ovulation test use and stress during subfertility evaluation: Subarm of a randomized controlled trial', Women's Health, vol. 15, http://dx.doi.org/10.1177/1745506519838363

Bertoldo MJ; Caldwell ASL; Riepsamen AH; Lin D; Gonzalez MB; Robker RL; Ledger WL; Gilchrist RB; Handelsman DJ; Walters KA, 2019, 'A hyperandrogenic environment causes intrinsic defects that are detrimental to follicular dynamics in a PCOS mouse model', Endocrinology, vol. 160, pp. 699 - 715, http://dx.doi.org/10.1210/en.2018-00966

Crawford GE; Ledger WL, 2019, 'In vitro fertilisation/intracytoplasmic sperm injection beyond 2020', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 126, pp. 237 - 243, http://dx.doi.org/10.1111/1471-0528.15526

Ledger W, 2018, 'Preface – Vol. 53', Best Practice and Research: Clinical Obstetrics and Gynaecology, vol. 53, pp. 1 - 2, http://dx.doi.org/10.1016/j.bpobgyn.2018.10.005

Anazodo A; Paula L; Logan S; Saunders C; Travaglia J; Gerstl B; Bradford N; Cohn R; Birdsall M; Barr R, 2018, 'How can we improve oncofertility care for patients? A systematic scoping review of current international practice and models of care.', Human Reproduction Update, http://dx.doi.org/10.1093/humupd/dmy038

Deans R; Vancaillie T; Ledger W; Liu J; Abbott JA, 2018, 'Live birth rate and obstetric complications following the hysteroscopic management of intrauterine adhesions including Asherman syndrome', Human Reproduction, vol. 33, pp. 1847 - 1853, http://dx.doi.org/10.1093/humrep/dey237

Vogt KS; Hughes J; Wilkinson A; Mahmoodi N; Skull J; Wood H; McDougall S; Slade P; Greenfield DM; Pacey A, 2018, 'Preserving fertility in women with cancer (PreFer): Decision-making and patient-reported outcomes in women offered egg and embryo freezing prior to cancer treatment', Psycho-Oncology, vol. 27, pp. 2725 - 2732, http://dx.doi.org/10.1002/pon.4866

Walters KA; Gilchrist RB; Ledger WL; Teede HJ; Handelsman DJ; Campbell RE, 2018, 'New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins', Trends in Endocrinology and Metabolism, vol. 29, pp. 841 - 852, http://dx.doi.org/10.1016/j.tem.2018.08.005

Bertoldo MJ; Walters KA; Ledger WL; Gilchrist RB; Mermillod P; Locatelli Y, 2018, 'In-vitro regulation of primordial follicle activation: challenges for fertility preservation strategies', Reproductive BioMedicine Online, vol. 36, pp. 491 - 499, http://dx.doi.org/10.1016/j.rbmo.2018.01.014

Storr A; Venetis C; Cooke S; Kilani S; Ledger W, 2018, 'Time-lapse algorithms and morphological selection of day-5 embryos for transfer: a preclinical validation study', Fertility and Sterility, vol. 109, pp. 276 - 283.e3, http://dx.doi.org/10.1016/j.fertnstert.2017.10.036

Nasioudis D; Linhares IM; Ledger WJ; Witkin SS, 2017, 'Bacterial vaginosis: a critical analysis of current knowledge', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 124, pp. 61 - 69, http://dx.doi.org/10.1111/1471-0528.14209

Patanwala IY; Lamvu G; Ledger WJ; Witzeman K; Marvel R; Rapkin A; Bongiovanni AM; Feranec J; Witkin SS, 2017, 'Catechol-O-methyltransferase gene polymorphism and vulvar pain in women with vulvodynia', American Journal of Obstetrics and Gynecology, vol. 216, pp. 395.e1 - 395.e6, http://dx.doi.org/10.1016/j.ajog.2016.10.020

Ledger WL, 2017, 'The HFEA should be regulating add-on treatments for IVF/ICSI', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 124, pp. 1850, http://dx.doi.org/10.1111/1471-0528.14670

Jones G; Hughes J; Mahmoodi N; Smith E; Skull J; Ledger W, 2017, 'What factors hinder the decision-making process for women with cancer and contemplating fertility preservation treatment?', Human Reproduction Update, vol. 23, pp. 433 - 457, http://dx.doi.org/10.1093/humupd/dmx009

Rodgers RJ; Reid GD; Koch J; Deans R; Ledger WL; Friedlander M; Gilchrist RB; Walters KA; Abbott JA, 2017, 'The safety and efficacy of controlled ovarian hyperstimulation for fertility preservation in women with early breast cancer: A systematic review', Human Reproduction, vol. 32, pp. 1033 - 1045, http://dx.doi.org/10.1093/humrep/dex027

McCredie S; Ledger W; Venetis CA, 2017, 'Anti-Müllerian hormone kinetics in pregnancy and post-partum: a systematic review', Reproductive BioMedicine Online, vol. 34, pp. 522 - 533, http://dx.doi.org/10.1016/j.rbmo.2017.02.005

Storr A; Venetis CA; Cooke S; Kilani S; Ledger W, 2017, 'Inter-observer and intra-observer agreement between embryologists during selection of a single Day 5 embryo for transfer: A multicenter study', Human Reproduction, vol. 32, pp. 307 - 314, http://dx.doi.org/10.1093/humrep/dew330

Ledger WL, 2017, 'A history of mental illness, but not of conception with assisted reproductive technology, puts patients at increased risk of severe postnatal depression', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 124, pp. 443, http://dx.doi.org/10.1111/1471-0528.13792

Ledger W; Johnson MH, 2016, 'One plus one equals two: Why fetal reduction is always a second-best solution', Reproductive BioMedicine Online, vol. 32, pp. 467 - 468, http://dx.doi.org/10.1016/j.rbmo.2016.03.002

Anazodo AC; Stern CJ; Mclachlan RI; Gerstl B; Agresta F; Cohn RJ; Jayasinghe Y; Wakefield CE; Daly G; Chan D, 2016, 'A study protocol for the australasian oncofertility registry: Monitoring referral patterns and the uptake, quality, and complications of fertility preservation strategies in Australia and New Zealand', Journal of Adolescent and Young Adult Oncology, vol. 5, pp. 215 - 225, http://dx.doi.org/10.1089/jayao.2015.0062

Anazodo AC; Gerstl B; Stern CJ; Mclachlan RI; Agresta F; Jayasinghe Y; Cohn RJ; Wakefield CE; Chapman M; Ledger W, 2016, 'Utilizing the experience of consumers in consultation to develop the australasian oncofertility consortium charter', Journal of Adolescent and Young Adult Oncology, vol. 5, pp. 232 - 239, http://dx.doi.org/10.1089/jayao.2015.0056

Chambers GM; Wand H; Macaldowie A; Chapman MG; Farquhar CM; Bowman M; Molloy D; Ledger W, 2016, 'Population trends and live birth rates associated with common ART treatment strategies', Human Reproduction, vol. 31, pp. 2632 - 2641, http://dx.doi.org/10.1093/humrep/dew232

Ledger WL; Turner MJ, 2016, 'Implementation of the findings of a national enquiry into the misdiagnosis of miscarriage in the Republic of Ireland: impact on quality of clinical care', Fertility and Sterility, vol. 105, pp. 417 - 422, http://dx.doi.org/10.1016/j.fertnstert.2015.11.002

Ledger WL; Turner MJ, 2016, 'Implementation of the findings of a national enquiry into the misdiagnosis of miscarriage in the Republic of Ireland: impact on quality of clinical care', Fertility and sterility, vol. 105, pp. 417 - 422, http://dx.doi.org/10.1016/j.fertnstert.2015.11.002

Lim HJ; Ledger W, 2016, 'Targeted therapy in ovarian cancer', Women's Health, vol. 12, pp. 363 - 378, http://dx.doi.org/10.2217/whe.16.4

McCullough K; Ledger W, 2016, 'Anti-Müllerian hormone is all you need: An assisted reproductive technology perspective in diagnosing polycystic ovary syndrome', Women's Health, vol. 12, pp. 263 - 265, http://dx.doi.org/10.2217/whe-2016-0005

Robertson DM; Gilchrist RB; Ledger WL; Baerwald A, 2016, 'Random start or emergency IVF/in vitro maturation: A new rapid approach to fertility preservation', Women's Health, vol. 12, pp. 339 - 349, http://dx.doi.org/10.2217/whe-2015-0001

Wang X; Gook DA; Walters KA; Anazodo A; Ledger WL; Gilchrist RB, 2016, 'Improving fertility preservation for girls and women by coupling oocyte in vitro maturation with existing strategies', Women's Health, vol. 12, pp. 275 - 278, http://dx.doi.org/10.2217/whe-2016-0019

Ataman LM; Rodrigues JK; Marinho RM; Caetano JPJ; Chehin MB; Alves da Motta EL; Serafini P; Suzuki N; Furui T; Takae S, 2016, 'Creating a Global Community of Practice for Oncofertility.', J Glob Oncol, vol. 2, pp. 83 - 96, http://dx.doi.org/10.1200/JGO.2015.000307

Ledger W, 2016, 'A history of mental illness, but not of conception with assisted reproductive technology, puts patients at increased risk of severe postnatal depression', BJOG: An International Journal of Obstetrics and Gynaecology, http://dx.doi.org/10.1111/1471-0528.13792

Ledger WL, 2016, 'Superfertility is more prevalent in obese women with recurrent early pregnancy miscarriage', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 123, pp. 223, http://dx.doi.org/10.1111/1471-0528.13815

Beghini J; Linhares IM; Giraldo PC; Ledger WJ; Witkin SS, 2015, 'Differential expression of lactic acid isomers, extracellular matrix metalloproteinase inducer, and matrix metalloproteinase-8 in vaginal fluid from women with vaginal disorders', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 122, pp. 1580 - 1585, http://dx.doi.org/10.1111/1471-0528.13072

Riepsamen A; Wu L; Lau L; Listijono D; Ledger W; Sinclair DA; Homer H, 2015, 'Erratum: Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes (PLoS ONE (2015) 10:5 (e0126194) DOI:10.1371/journal.pone.0126194)', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0126194

Coughlan C; Clarke H; Cutting R; Saxton J; Waite S; Ledger W; Li T; Pacey AA, 2015, 'Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage', Asian Journal of Andrology, vol. 17, pp. 681 - 685, http://dx.doi.org/10.4103/1008-682X.144946

Riepsamen A; Wu L; Lau L; Listijono D; Ledger W; Sinclair D; Homer H, 2015, 'Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0130058

Jones G; Carlton J; Weddell S; Johnson S; Ledger WL, 2015, 'Women's experiences of ovulation testing: A qualitative analysis', Reproductive Health, vol. 12, http://dx.doi.org/10.1186/s12978-015-0103-y

Jones GL; Jacques RM; Thompson J; Wood HJ; Hughes J; Ledger W; Alazzam M; Radley SC; Tidy JA, 2015, 'The impact of surgery for vulval cancer upon health-related quality of life and pelvic floor outcomes during the first year of treatment: A longitudinal, mixed methods study', Psycho-Oncology, http://dx.doi.org/10.1002/pon.3992

Ledger W, 2015, 'Letter to the editor', Journal of Assisted Reproduction and Genetics, vol. 32, pp. 1161, http://dx.doi.org/10.1007/s10815-015-0526-y

Storr A; Venetis CA; Cooke S; Susetio D; Kilani S; Ledger W, 2015, 'Morphokinetic parameters using time-lapse technology and day 5 embryo quality: a prospective cohort study', Journal of Assisted Reproduction and Genetics, vol. 32, pp. 1151 - 1160, http://dx.doi.org/10.1007/s10815-015-0534-y

Nesbitt-Hawes EM; Campbell N; Maley PE; Won H; Hooshmand D; Henry A; Ledger W; Abbott JA, 2015, 'The Surgical Treatment of Severe Endometriosis Positively Affects the Chance of Natural or Assisted Pregnancy Postoperatively', BioMed Research International, vol. 2015, http://dx.doi.org/10.1155/2015/438790

Aitchison LP; Flint J; Nesbitt-Hawes E; Ledger W; Abbott J, 2015, 'a feasibility study determining surgical ergonomics in a live surgical setting', Journal of Minimally Invasive Gynecology, vol. 22, pp. 626 - 630, http://dx.doi.org/10.1016/j.jmig.2015.01.022

Refaat B; Dalton E; Ledger WL, 2015, 'Ectopic pregnancy secondary to in vitro fertilisation-embryo transfer: Pathogenic mechanisms and management strategies', Reproductive Biology and Endocrinology, vol. 13, http://dx.doi.org/10.1186/s12958-015-0025-0

Scholten I; Chambers GM; Van Loendersloot L; Van Der Veen F; Repping S; Gianotten J; Hompes PGA; Ledger W; Mol BWJ, 2015, 'Impact of assisted reproductive technology on the incidence of multiple-gestation infants: A population perspective', Fertility and Sterility, vol. 103, pp. 179 - 183, http://dx.doi.org/10.1016/j.fertnstert.2014.09.033

Pacey AA; Povey AC; Clyma J-A; McNamee R; Moore HD; Baillie H; Cherry NM; Participating Centres of Chaps-UK, 2014, 'Modifiable and non-modifiable risk factors for poor sperm morphology.', Hum Reprod, vol. 29, pp. 1629 - 1636, http://dx.doi.org/10.1093/humrep/deu116

Greenfield DM; Boland E; Ezaydi Y; Ross RJM; Ahmedzai SH; Snowden JA; Late Effects Group, 2014, 'Endocrine, metabolic, nutritional and body composition abnormalities are common in advanced intensively-treated (transplanted) multiple myeloma.', Bone Marrow Transplant, vol. 49, pp. 907 - 912, http://dx.doi.org/10.1038/bmt.2014.63

Li Z; Wang YA; Ledger W; Edgar DH; Sullivan EA, 2014, 'Clinical outcomes following cryopreservation of blastocysts by vitrification or slow freezing: A population-based cohort study', Human Reproduction, vol. 29, pp. 2794 - 2801, http://dx.doi.org/10.1093/humrep/deu246

Atkinson P; Koch J; Ledger WL, 2014, 'GnRH agonist trigger and a freeze-all strategy to prevent ovarian hyperstimulation syndrome: A retrospective study of OHSS risk and pregnancy rates', Australian and New Zealand Journal of Obstetrics and Gynaecology, vol. 54, pp. 581 - 585, http://dx.doi.org/10.1111/ajo.12277

Metwally M; Preece R; Thomas J; Ledger W; Li TC, 2014, 'A proteomic analysis of the endometrium in obese and overweight women with recurrent miscarriage: Preliminary evidence for an endometrial defect', Reproductive Biology and Endocrinology, vol. 12, http://dx.doi.org/10.1186/1477-7827-12-75

Chambers GM; Ledger W, 2014, 'The economic implications of multiple pregnancy following ART', Seminars in Fetal and Neonatal Medicine, vol. 19, pp. 254 - 261, http://dx.doi.org/10.1016/j.siny.2014.04.004

Li Z; Wang YA; Ledger W; Sullivan EA, 2014, 'Birthweight percentiles by gestational age for births following assisted reproductive technology in Australia and New Zealand, 2002-2010', Human Reproduction, vol. 29, pp. 1787 - 1800, http://dx.doi.org/10.1093/humrep/deu120

Atkinson P; Koch J; Susic D; Ledger WL, 2014, 'GnRH agonist triggers and their use in assisted reproductive technology: The past, the present and the future', Women's Health, vol. 10, pp. 267 - 276, http://dx.doi.org/10.2217/whe.14.14

Han X; McShane M; Sahertian R; White C; Ledger W, 2014, 'Pre-mixing serum samples with assay buffer is a prerequisite for reproducible anti-Müllerian hormone measurement using the Beckman Coulter Gen II assay', Human Reproduction, vol. 29, pp. 1042 - 1048, http://dx.doi.org/10.1093/humrep/deu050

Cheong YC; Reading I; Bailey S; Sadek K; Ledger W; Li TC, 2014, 'Should women with chronic pelvic pain have adhesiolysis?', BMC Women's Health, vol. 14, http://dx.doi.org/10.1186/1472-6874-14-36

Coughlan C; Yuan X; Demirol A; Ledger W; Li TC, 2014, 'Factors affecting the outcome of "Endometrial Scratch" in women with recurrent implantation failure', Journal of Reproductive Medicine, vol. 59, pp. 39 - 43

Coughlan C; Walters S; Ledger W; Li TC, 2014, 'A comparison of psychological stress among women with and without reproductive failure', International Journal of Gynecology and Obstetrics, vol. 124, pp. 143 - 147, http://dx.doi.org/10.1016/j.ijgo.2013.08.006

Ledger WL, 2014, 'Measurement of antimüllerian hormone: not as straightforward as it seems', Fertility and Sterility, vol. 101, pp. 339 - 339, http://dx.doi.org/10.1016/j.fertnstert.2013.11.017

Cheong YC; Dix S; Hung Yu Ng E; Ledger WL; Farquhar C, 2013, 'Acupuncture and assisted reproductive technology', Cochrane Database of Systematic Reviews, vol. 2013, http://dx.doi.org/10.1002/14651858.CD006920.pub3

Wong MYW; Ledger WL, 2013, 'Is ICSI Risky?', Obstet Gynecol Int, vol. 2013, pp. 473289, http://dx.doi.org/10.1155/2013/473289

Bowes H; Jones G; Wood H; Thompson J; Alazzam M; Tidy J; Hinchliff S; Ledger W, 2013, 'Understanding the impact of the treatment pathway upon the health-related quality of life of women with newly diagnosed endometrial cancer - A qualitative study', European Journal of Oncology Nursing, http://dx.doi.org/10.1016/j.ejon.2013.10.007

Coughlan C; Cutting R; Li TC; Ledger W; Wang Q; Liu F; Demirol A; Gurgan T; Ong K; Sallam H, 2013, 'Recurrent implantation failure: definition and management', Reproductive BioMedicine Online, http://dx.doi.org/10.1016/j.rbmo.2013.08.011

Coughlan C; Sinagra M; Ledger W; Li TC; Laird S, 2013, 'Endometrial integrin expression in women with recurrent implantation failure after in vitro fertilization and its relationship to pregnancy outcome', Fertility and Sterility, vol. 100, pp. 825 - 830.e2, http://dx.doi.org/10.1016/j.fertnstert.2013.05.007

Levy MJ; Ledger W; Kolibianakis EM; IJzerman-Boon PC; Gordon K, 2013, 'Is it possible to reduce the incidence of weekend oocyte retrievals in GnRH antagonist protocols', Reproductive BioMedicine Online, vol. 26, pp. 50 - 58, http://dx.doi.org/10.1016/j.rbmo.2012.09.014

Tiplady S; Jones G; Campbell M; Johnson S; Ledger W, 2013, 'Home ovulation tests and stress in women trying to conceive: A randomized controlled trial', Human Reproduction, vol. 28, pp. 138 - 151, http://dx.doi.org/10.1093/humrep/des372

Koch J; Ledger W, 2013, 'Ovarian stimulation protocols for onco-fertilty patients', Journal of Assisted Reproduction and Genetics, vol. 30, pp. 203 - 206, http://dx.doi.org/10.1007/s10815-013-9947-7

Nesbitt-Hawes EM; Maley PE; Won HR; Law KSK; Zhang CS; Lyons SD; Ledger W; Abbott JA, 2013, 'Laparoscopic Subtotal Hysterectomy: Evidence and Techniques', Journal of Minimally Invasive Gynecology, vol. 20, pp. 424 - 434, http://dx.doi.org/10.1016/j.jmig.2013.01.009

Li W; Ma N; Laird SM; Ledger WL; Li TC, 2013, 'The relationship between serum prolactin concentration and pregnancy outcome in women with unexplained recurrent miscarriage', Journal of Obstetrics and Gynaecology, vol. 33, pp. 285 - 288, http://dx.doi.org/10.3109/01443615.2012.759916

Chambers GM; Wang YA; Chapman MG; Hoang VP; Sullivan EA; Abdalla HI; Ledger W, 2013, 'What can we learn from a decade of promoting safe embryo transfer practices? A comparative analysis of policies and outcomes in the UK and Australia, 2001-2010', Human Reproduction, vol. 28, pp. 1679 - 1686, http://dx.doi.org/10.1093/humrep/det080

Povey AC; Clyma J-A; McNamee R; Moore HD; Baillie H; Pacey AA; Cherry NM; Participating Centres of Chaps-uk, 2012, 'Modifiable and non-modifiable risk factors for poor semen quality: a case-referent study.', Hum Reprod, vol. 27, pp. 2799 - 2806, http://dx.doi.org/10.1093/humrep/des183

Ledger W, 2012, 'The Older Patient', Assisted Reproduction Techniques: Challenges and Management Options, pp. 142 - 145, http://dx.doi.org/10.1002/9781444398854.ch36

Zinaman M; Johnson S; Ellis J; Ledger W, 2012, 'Accuracy of perception of ovulation day in women trying to conceive', Current Medical Research and Opinion, vol. 28, pp. 749 - 754, http://dx.doi.org/10.1185/03007995.2012.681638

Costello MF; Ledger WL, 2012, 'Evidence-based management of infertility in women with polycystic ovary syndrome using surgery or assisted reproductive technology', Women's Health, vol. 8, pp. 291 - 300, http://dx.doi.org/10.2217/whe.12.7

Costello MF; Ledger WL, 2012, 'Evidence-based lifestyle and pharmacological management of infertility in women with polycystic ovary syndrome', Women's Health, vol. 8, pp. 277 - 290, http://dx.doi.org/10.2217/whe.12.14

Li W; Newell-Price J; Jones GL; Ledger WL; Li TC, 2012, 'Relationship between psychological stress and recurrent miscarriage', Reproductive BioMedicine Online, vol. 25, pp. 180 - 189, http://dx.doi.org/10.1016/j.rbmo.2012.03.012

Refaat B; Simpson H; Britton E; Biswas J; Wells M; Aplin JD; Ledger W, 2012, 'Why does the fallopian tube fail in ectopic pregnancy? the role of activins, inducible nitric oxide synthase, and MUC1 in ectopic implantation', Fertility and Sterility, vol. 97, pp. 1115 - 1123, http://dx.doi.org/10.1016/j.fertnstert.2012.02.035

Fauser BCJM; Alper MM; Ledger W; Schoolcraft WB; Zandvliet A; Mannaerts BMJL; Engage Investigators, 2011, 'Pharmacokinetics and follicular dynamics of corifollitropin alfa versus recombinant FSH during ovarian stimulation for IVF.', Reprod Biomed Online, vol. 22 Suppl 1, pp. S23 - S31, http://dx.doi.org/10.1016/S1472-6483(11)60006-0

Al-Azemi M; Killick SR; Duffy S; Pye C; Refaat B; Hill N; Ledger W, 2011, 'Multi-marker assessment of ovarian reserve predicts oocyte yield after ovulation induction', Human Reproduction, vol. 26, pp. 414 - 422, http://dx.doi.org/10.1093/humrep/deq339

Metwally M; Ledger WL, 2011, 'Induction of ovulation', Obstetrics, Gynaecology and Reproductive Medicine, vol. 21, pp. 47 - 51, http://dx.doi.org/10.1016/j.ogrm.2010.11.004

Amer S; Li TC; Samuelson C; Ledger W, 2011, 'The impact of insulin resistance on the outcome of laparoscopic ovarian diathermy in women with polycystic ovarian syndrome', Acta Obstetricia et Gynecologica Scandinavica, vol. 90, pp. 338 - 343, http://dx.doi.org/10.1111/j.1600-0412.2010.01061.x

Lee VCY; Ledger W, 2011, 'Aromatase inhibitors for ovulation induction and ovarian stimulation', Clinical Endocrinology, vol. 74, pp. 537 - 546, http://dx.doi.org/10.1111/j.1365-2265.2011.04006.x

Metwally M; Ledger WL, 2011, 'Long-term complications of assisted reproductive technologies', Human Fertility, vol. 14, pp. 77 - 87, http://dx.doi.org/10.3109/14647273.2011.580550

Cowell PE; Ledger WL; Wadnerkar MB; Skilling FM; Whiteside SP, 2011, 'Hormones and dichotic listening: Evidence from the study of menstrual cycle effects', Brain and Cognition, vol. 76, pp. 256 - 262, http://dx.doi.org/10.1016/j.bandc.2011.03.010

Ledger WL; Fauser BCJM; Devroey P; Zandvliet AS; Mannaerts BMJL, 2011, 'Corifollitropin alfa doses based on body weight: Clinical overview of drug exposure and ovarian response', Reproductive BioMedicine Online, vol. 23, pp. 150 - 159, http://dx.doi.org/10.1016/j.rbmo.2011.04.002

Jones GL; Hall JM; Lashen HL; Balen AH; Ledger WL, 2011, 'Health-Related Quality of Life Among Adolescents with Polycystic Ovary Syndrome', JOGNN - Journal of Obstetric, Gynecologic, and Neonatal Nursing, vol. 40, pp. 577 - 588, http://dx.doi.org/10.1111/j.1552-6909.2011.01279.x

Ledger W; Chapman M, 2011, 'Barriers to conducting clinical research in reproductive medicine: Australia and the United Kingdom', Fertility and Sterility, vol. 96, pp. 813 - 816, http://dx.doi.org/10.1016/j.fertnstert.2011.09.014

Refaat B; Ledger W, 2011, 'The expression of activins, their type II receptors and follistatin in human Fallopian tube during the menstrual cycle and in pseudo-pregnancy', Human Reproduction, vol. 26, pp. 3346 - 3354, http://dx.doi.org/10.1093/humrep/der331

Ledger WJ, 2010, 'Antimicrobial prophylaxis for cesarean delivery before skin incision', Obstetrics and Gynecology, vol. 115, pp. 187 - 188, http://dx.doi.org/10.1097/AOG.0b013e3181c8afdc

Weinreb EB; Cholst IN; Ledger WJ; Danis RB; Rosenwaks Z, 2010, 'Should all oocyte donors receive prophylactic antibiotics for retrieval?', Fertility and Sterility, vol. 94, pp. 2935 - 2937, http://dx.doi.org/10.1016/j.fertnstert.2010.05.054

Ledger WL, 2010, 'Format and structure of the new part 2 MRCOG examination: I', Obstetrics, Gynaecology and Reproductive Medicine, vol. 20, pp. 27 - 28, http://dx.doi.org/10.1016/j.ogrm.2009.10.006

Al-Azemi M; Refaat B; Amer S; Ola B; Chapman N; Ledger W, 2010, 'The expression of inducible nitric oxide synthase in the human fallopian tube during the menstrual cycle and in ectopic pregnancy', Fertility and Sterility, vol. 94, pp. 833 - 840, http://dx.doi.org/10.1016/j.fertnstert.2009.04.020

Ledger WL, 2010, 'Format and structure of the new Part 2 MRCOG examination: II', Obstetrics, Gynaecology and Reproductive Medicine, vol. 20, pp. 63 - 64, http://dx.doi.org/10.1016/j.ogrm.2009.11.004

Connolly MP; Ledger W; Postma MJ, 2010, 'Economics of assisted reproduction: Access to fertility treatments and valuing live births in economic terms', Human Fertility, vol. 13, pp. 13 - 18, http://dx.doi.org/10.3109/14647270903401747

Cheong Y; Nardo LG; Rutherford T; Ledger W, 2010, 'Acupuncture and herbal medicine in in vitro fertilisation: A review of the evidence for clinical practice', Human Fertility, vol. 13, pp. 3 - 12, http://dx.doi.org/10.3109/14647270903438830

Waylen AL; Jones GL; Ledger WL, 2010, 'Effect of cigarette smoking upon reproductive hormones in women of reproductive age: A retrospective analysis', Reproductive BioMedicine Online, vol. 20, pp. 861 - 865, http://dx.doi.org/10.1016/j.rbmo.2010.02.021

Metwally M; Saravelos SH; Ledger WL; Li TC, 2010, 'Body mass index and risk of miscarriage in women with recurrent miscarriage', Fertility and Sterility, vol. 94, pp. 290 - 295, http://dx.doi.org/10.1016/j.fertnstert.2009.03.021

Fauser BCJM; Nargund G; Andersen AN; Norman R; Tarlatzis B; Boivin J; Ledger W, 2010, 'Mild ovarian stimulation for IVF: 10 years later', Human Reproduction, vol. 25, pp. 2678 - 2684, http://dx.doi.org/10.1093/humrep/deq247

Fauser BCJM; Alper MM; Ledger W; Schoolcraft WB; Zandvliet A; Mannaerts BMJL, 2010, 'Pharmacokinetics and follicular dynamics of corifollitropin alfa versus recombinant FSH during ovarian stimulation for IVF', Reproductive BioMedicine Online, vol. 21, pp. 593 - 601, http://dx.doi.org/10.1016/j.rbmo.2010.06.032

Ledger WL, 2010, 'Clinical utility of measurement of anti-müllerian hormone in reproductive endocrinology', Journal of Clinical Endocrinology and Metabolism, vol. 95, pp. 5144 - 5154, http://dx.doi.org/10.1210/jc.2010-0701

Jones GL; Palep-Singh M; Ledger WL; Balen AH; Jenkinson C; Campbell MJ; Lashen H, 2010, 'Do South Asian women with PCOS have poorer health-related quality of life than Caucasian women with PCOS? A comparative cross-sectional study', Health and Quality of Life Outcomes, vol. 8, http://dx.doi.org/10.1186/1477-7525-8-149

Ledger WL, 2009, 'Complications of laparoscopic surgery', Obstetrics, Gynaecology and Reproductive Medicine, vol. 19, pp. 193 - 196, http://dx.doi.org/10.1016/j.ogrm.2009.03.004

Ledger WL, 2009, 'Medicolegal aspects of reproductive medicine', Clinical Risk, vol. 15, pp. 197 - 200, http://dx.doi.org/10.1258/cr.2009.090061

Al-Azemi M; Refaat B; Aplin J; Ledger W, 2009, 'The expression of MUC1 in human Fallopian tube during the menstrual cycle and in ectopic pregnancy', Human Reproduction, vol. 24, pp. 2582 - 2587, http://dx.doi.org/10.1093/humrep/dep233

Al-Azemi M; Jones G; Sirkeci F; Walters S; Houdmont M; Ledger W, 2009, 'Immediate and delayed add-back hormonal replacement therapy during ultra long GnRH agonist treatment of chronic cyclical pelvic pain', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 116, pp. 1646 - 1656, http://dx.doi.org/10.1111/j.1471-0528.2009.02319.x

Amer SA; Li TC; Metwally M; Emarh M; Ledger WL, 2009, 'Randomized controlled trial comparing laparoscopic ovarian diathermy with clomiphene citrate as a first-line method of ovulation induction in women with polycystic ovary syndrome', Human Reproduction, vol. 24, pp. 219 - 225, http://dx.doi.org/10.1093/humrep/den325

Waylen AL; Metwally M; Jones GL; Wilkinson AJ; Ledger WL, 2009, 'Effects of cigarette smoking upon clinical outcomes of assisted reproduction: A meta-analysis', Human Reproduction Update, vol. 15, pp. 31 - 44, http://dx.doi.org/10.1093/humupd/dmn046

Ghobadi C; Mirhosseini N; Shiran MR; Moghadamnia A; Lennard MS; Ledger WL; Rostami-Hodjegan A, 2009, 'Single-dose pharmacokinetic study of clomiphene citrate isomers in anovular patients with polycystic ovary disease', Journal of Clinical Pharmacology, vol. 49, pp. 147 - 154, http://dx.doi.org/10.1177/0091270008328096

Connolly M; Gallo F; Hoorens S; Ledger W, 2009, 'Assessing long-run economic benefits attributed to an IVF-conceived singleton based on projected lifetime net tax contributions in the UK', Human Reproduction, vol. 24, pp. 626 - 632, http://dx.doi.org/10.1093/humrep/den435

Metwally M; Amer S; Li TC; Ledger WL, 2009, 'An RCT of metformin versus orlistat for the management of obese anovulatory women', Human Reproduction, vol. 24, pp. 966 - 975, http://dx.doi.org/10.1093/humrep/den454

Ghobadi C; Amer S; Lashen H; Lennard MS; Ledger WL; Rostami-Hodjegan A, 2009, 'Evaluation of the relationship between plasma concentrations of en- and zuclomiphene and induction of ovulation in anovulatory women being treated with clomiphene citrate', Fertility and Sterility, vol. 91, pp. 1135 - 1140, http://dx.doi.org/10.1016/j.fertnstert.2008.01.058

Ledger WL, 2009, 'Demographics of infertility', Reproductive BioMedicine Online, vol. 18, http://dx.doi.org/10.1016/S1472-6483(10)60442-7

Devroey P; Aboulghar M; Garcia-Velasco J; Griesinger G; Humaidan P; Kolibianakis E; Ledger W; Tomás C; Fauser BCJM, 2009, 'Improving the patient's experience of IVF/ICSI: A proposal for an ovarian stimulation protocol with GnRH antagonist co-treatment', Human Reproduction, vol. 24, pp. 764 - 774, http://dx.doi.org/10.1093/humrep/den468

Ledger W, 2009, 'Pregnancy in the over 40s', Obstetrics, Gynaecology and Reproductive Medicine, vol. 19, pp. 142 - 143, http://dx.doi.org/10.1016/j.ogrm.2009.01.002

Lã FMB; Howard DM; Ledger W; Davidson JW; Jones G, 2009, 'Oral contraceptive pill containing drospirenone and the professional voice: An electrolaryngographic analysis', Logopedics Phoniatrics Vocology, vol. 34, pp. 11 - 19, http://dx.doi.org/10.1080/14015430802538879

Ledger W; Wiebinga C; Anderson P; Irwin D; Holman A; Lloyd A, 2009, 'Costs and outcomes associated with IVF using recombinant FSH.', Reproductive biomedicine online, vol. 19, pp. 337 - 342

Refaat B; Al-Azemi M; Geary I; Eley A; Ledger W, 2009, 'Role of activins and inducible nitric oxide in the pathogenesis of ectopic pregnancy in patients with or without Chlamydia trachomatis infection', Clinical and Vaccine Immunology, vol. 16, pp. 1493 - 1503, http://dx.doi.org/10.1128/CVI.00221-09

Connolly MP; Griesinger G; Ledger W; Postma MJ, 2009, 'The impact of introducing patient co-payments in Germany on the use of IVF and ICSI: A price-elasticity of demand assessment', Human Reproduction, vol. 24, pp. 2796 - 2800, http://dx.doi.org/10.1093/humrep/dep260

Amer SA; Li TC; Ledger WL, 2009, 'The value of measuring anti-Müllerian hormone in women with anovulatory polycystic ovary syndrome undergoing laparoscopic ovarian diathermy', Human Reproduction, vol. 24, pp. 2760 - 2766, http://dx.doi.org/10.1093/humrep/dep271

Ledger WL, 2009, 'Supine positioning after intrauterine insemination', BMJ (Online), vol. 339, pp. 1040, http://dx.doi.org/10.1136/bmj.b4274

Coughlan C; Ledger WL, 2009, 'In-vitro fertilisation', Poloznictwo Ginekologia i Medycyna Rozrodu, vol. 3, pp. 119 - 128

Ledger WL, 2009, 'Complications of laparoscopic surgery', Poloznictwo Ginekologia i Medycyna Rozrodu, vol. 3, pp. 494 - 499

Ledger W, 2009, 'Pregnancy in the over 40s', Poloznictwo Ginekologia i Medycyna Rozrodu, vol. 3, pp. 405 - 406

Ledger WJ, 2008, 'Perinatal infections and fetal/neonatal brain injury', Current Opinion in Obstetrics and Gynecology, vol. 20, pp. 120 - 124, http://dx.doi.org/10.1097/GCO.0b013e3282f734db

Farage MA; Miller KW; Ledger WJ, 2008, 'Determining the cause of vulvovaginal symptoms', Obstetrical and Gynecological Survey, vol. 63, pp. 445 - 464, http://dx.doi.org/10.1097/OGX.0b013e318172ee25

Ziebe S; Devroey P; State of ART 2007 Workshop Group, 2008, 'Assisted reproductive technologies are an integrated part of national strategies addressing demographic and reproductive challenges.', Hum Reprod Update, vol. 14, pp. 583 - 592, http://dx.doi.org/10.1093/humupd/dmn038

Refaat B; Amer S; Ola B; Chapman N; Ledger W, 2008, 'The expression of activin-βA- and -βB-subunits, follistatin, and activin type II receptors in fallopian tubes bearing an ectopic pregnancy', Journal of Clinical Endocrinology and Metabolism, vol. 93, pp. 293 - 299, http://dx.doi.org/10.1210/jc.2007-1654

Connolly M; Hoorens S; Ledger W, 2008, 'Money in - Babies out: Assessing the long-term economic impact of IVF-conceived children', Journal of Medical Ethics, vol. 34, pp. 653 - 654, http://dx.doi.org/10.1136/jme.2007.022475

Jones GL; Balen AH; Ledger WL, 2008, 'Health-related quality of life in PCOS and related infertility: How can we assess this?', Human Fertility, vol. 11, pp. 173 - 185, http://dx.doi.org/10.1080/14647270802078179

Jones GL; Hall JM; Balen AH; Ledger WL, 2008, 'Health-related quality of life measurement in women with polycystic ovary syndrome: A systematic review', Human Reproduction Update, vol. 14, pp. 15 - 25, http://dx.doi.org/10.1093/humupd/dmm030

Prakash A; Tuckerman E; Laird S; Ola B; Li TC; Ledger WL, 2008, 'A preliminary study comparing the endometrial expression of inhibin, activin and follistatin in women with a history of implantation failure after IVF treatment and a control group', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 115, pp. 532 - 536, http://dx.doi.org/10.1111/j.1471-0528.2007.01624.x

Metwally M; Ledger WL; Li TC, 2008, 'Reproductive endocrinology and clinical aspects of obesity in women', Annals of the New York Academy of Sciences, vol. 1127, pp. 140 - 146, http://dx.doi.org/10.1196/annals.1434.000

Jones GL; Ledger W; Mitchell C, 2008, '10-Minute consultation: Suspected premature menopause', BMJ, vol. 336, pp. 833, http://dx.doi.org/10.1136/bmj.39371.652604.94

Dixon S; Faghih Nasiri F; Ledger WL; Lenton EA; Duenas A; Sutcliffe P; Chilcott JB, 2008, 'Cost-effectiveness analysis of different embryo transfer strategies in England', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 115, pp. 758 - 766, http://dx.doi.org/10.1111/j.1471-0528.2008.01667.x

Cheong YC; Hung Yu Ng E; Ledger WL, 2008, 'Acupuncture and assisted conception', Cochrane Database of Systematic Reviews, http://dx.doi.org/10.1002/14651858.CD006920

Metwally M; Ong KJ; Ledger WL; Li TC, 2008, 'Does high body mass index increase the risk of miscarriage after spontaneous and assisted conception? A meta-analysis of the evidence', Fertility and Sterility, vol. 90, pp. 714 - 726, http://dx.doi.org/10.1016/j.fertnstert.2007.07.1290

Jones GL; Ledger W; Mitchell C, 2008, 'Suspected premature menopause', Praxis, vol. 97, pp. 1089 - 1090

Coughlan C; Ledger WL, 2008, 'In-vitro fertilisation', Obstetrics, Gynaecology and Reproductive Medicine, vol. 18, pp. 300 - 306, http://dx.doi.org/10.1016/j.ogrm.2008.08.009

Absolom K; Eiser C; Turner L; Ledger W; Ross R; Davies H; Coleman R; Hancock B; Snowden J; Greenfield D, 2008, 'Ovarian failure following cancer treatment: Current management and quality of life', Human Reproduction, vol. 23, pp. 2506 - 2512, http://dx.doi.org/10.1093/humrep/den285

Sziller I; Babula O; Ujházy A; Nagy B; Hupuczi P; Papp Z; Linhares IM; Ledger WJ; Witkin SS, 2007, 'Chlamydia trachomatis infection, Fallopian tube damage and a mannose-binding lectin codon 54 gene polymorphism', Human Reproduction, vol. 22, pp. 1861 - 1865, http://dx.doi.org/10.1093/humrep/dem107

Ong K; Theodorou E; Cheong YC; Skull J; Ledger WL, 2007, 'Outcomes of follicular reduction (FR) at stimulated intrauterine insemination (SIUI) in a nested case controlled study', AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, vol. 47, pp. A23 - A23, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000249997000065&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Cheong Y; Ledger W, 2007, 'Late reproductive effects of cancer treatment', Obstetrics, Gynaecology and Reproductive Medicine, vol. 17, pp. 22 - 24, http://dx.doi.org/10.1016/j.ogrm.2006.12.004

Ledger W; Murphy M; Hodges P, 2007, 'Format and structure of the Part 2 MRCOG examination', Obstetrics, Gynaecology and Reproductive Medicine, vol. 17, pp. 62 - 64, http://dx.doi.org/10.1016/j.ogrm.2006.12.011

Cheong Y; Ledger WL, 2007, 'Hysteroscopy and hysteroscopic surgery', Obstetrics, Gynaecology and Reproductive Medicine, vol. 17, pp. 99 - 104, http://dx.doi.org/10.1016/j.ogrm.2007.02.001

Metwally M; Li TC; Ledger WL, 2007, 'The impact of obesity on female reproductive function', Obesity Reviews, vol. 8, pp. 515 - 523, http://dx.doi.org/10.1111/j.1467-789X.2007.00406.x

Ledger W, 2007, 'Challenges and opportunities for assisted reproduction in the 21st century', Journal de Gynecologie Obstetrique et Biologie de la Reproduction, vol. 36, pp. 2 - 3, http://dx.doi.org/10.1016/S0368-2315(07)80002-0

Amer SA; Laird S; Ledger WL; Li TC, 2007, 'Effect of laparoscopic ovarian diathermy on circulating inhibin B in women with anovulatory polycystic ovary syndrome', Human Reproduction, vol. 22, pp. 389 - 394, http://dx.doi.org/10.1093/humrep/del373

Ghobadi C; Nguyen TH; Lennard MS; Amer S; Rostami-Hodjegan A; Ledger WL, 2007, 'Evaluation of an existing nomogram for predicting the response to clomiphene citrate', Fertility and Sterility, vol. 87, pp. 597 - 602, http://dx.doi.org/10.1016/j.fertnstert.2006.10.002

Metwally M; Tuckerman EM; Laird SM; Ledger WL; Li TC, 2007, 'Impact of high body mass index in endometrial morphology and function in the peri-implantation period in women with recurrent miscarriage', Reproductive BioMedicine Online, vol. 14, pp. 328 - 334, http://dx.doi.org/10.1016/S1472-6483(10)60875-9

McIlveen M; Skull JD; Ledger WL, 2007, 'Evaluation of the utility of multiple endocrine and ultrasound measures of ovarian reserve in the prediction of cycle cancellation in a high-risk IVF population', Human Reproduction, vol. 22, pp. 778 - 785, http://dx.doi.org/10.1093/humrep/del435

Ledger WL, 2007, 'Favourable outcomes from "mild" in-vitro fertilisation', Lancet, vol. 369, pp. 717 - 718, http://dx.doi.org/10.1016/S0140-6736(07)60332-8

Amer SA; Ledger WL; Li TC, 2007, 'Reply: Effect of laparoscopic ovarian diathermy on circulating inhibin B in women with anovulatory polycystic ovary syndrome [4]', Human Reproduction, vol. 22, pp. 2073 - 2074, http://dx.doi.org/10.1093/humrep/dem132

Ong KJ; Metwally M; Ledger WL, 2007, 'Uterine artery embolization and future fertility potential', Women's Health, vol. 3, pp. 449 - 453, http://dx.doi.org/10.2217/17455057.3.4.449

Lã FMB; Ledger WL; Davidson JW; Howard DM; Jones GL, 2007, 'The Effects of a Third Generation Combined Oral Contraceptive Pill on the Classical Singing Voice', Journal of Voice, vol. 21, pp. 754 - 761, http://dx.doi.org/10.1016/j.jvoice.2006.05.009

Metwally M; Cutting R; Tipton A; Skull J; Ledger WL; Li TC, 2007, 'Effect of increased body mass index on oocyte and embryo quality in IVF patients', Reproductive BioMedicine Online, vol. 15, pp. 532 - 538, http://dx.doi.org/10.1016/S1472-6483(10)60385-9

Lä F; Davidson JW; Ledger W; Howard D; Jones G, 2007, 'A case-study on the effects of the menstrual cycle and the use of a combined oral contraceptive pill on the performance of a western classical singer: An objective and subjective overview', Musicae Scientiae, vol. 11, pp. 85 - 107

Ong KJ; Theodoru E; Ledger W, 2006, 'Long-term consequence of polycystic ovarian syndrome', Current Obstetrics and Gynaecology, vol. 16, pp. 333 - 336, http://dx.doi.org/10.1016/j.curobgyn.2006.09.002

Prakash A; Laird S; Li TC; Ledger WL, 2006, 'Preliminary prospective study of the endocrinology of conception cycles and early pregnancy in women with antiphospholipid syndrome treated with low molecular weight heparin', Fertility and Sterility, vol. 85, pp. 165 - 170, http://dx.doi.org/10.1016/j.fertnstert.2005.07.1288

Ledger WL; Anumba D; Marlow N; Thomas CM; Wilson ECF, 2006, 'The costs to the NHS of multiple births after IVF treatment in the UK', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 113, pp. 21 - 25, http://dx.doi.org/10.1111/j.1471-0528.2005.00790.x

Jones GL; Ledger W; Bonnett TJ; Radley S; Parkinson N; Kennedy SH, 2006, 'The impact of treatment for gynecological cancer on health-related quality of life (HRQoL): A systematic review', American Journal of Obstetrics and Gynecology, vol. 194, pp. 26 - 42, http://dx.doi.org/10.1016/j.ajog.2005.04.060

Prakash A; Li TC; Laird S; Nargund G; Ledger WL, 2006, 'Absence of follicular phase defect in women with recurrent miscarriage', Fertility and Sterility, vol. 85, pp. 1784 - 1790, http://dx.doi.org/10.1016/j.fertnstert.2005.11.045

Tarlatzis BC; Fauser BC; Kolibianakis EM; Diedrich K; Devroey P; Aboulghar M; Collins J; Crosignani PG; Griesinger G; Kol S, 2006, 'GnRH antagonists in ovarian stimulation for IVF', Human Reproduction Update, vol. 12, pp. 333 - 340, http://dx.doi.org/10.1093/humupd/dml001

Kennedy R; Kingsland C; Rutherford A; Hamilton M; Ledger W, 2006, 'Implementation of the NICE guideline - Recommendations from the British Fertility Society for national criteria for NHS funding of assisted conception', Human Fertility, vol. 9, pp. 181 - 189, http://dx.doi.org/10.1080/14647270600908411

Seng SW; Ong KJ; Ledger WL, 2006, 'Gonadotropin-releasing hormone antagonist in in vitro fertilization superovulation', Women's Health, vol. 2, pp. 881 - 888, http://dx.doi.org/10.2217/17455057.2.6.881

Nguyen TH; Lennard MS; Ghobadi C; Rostami-Hodjegan A; Ledger WL, 2006, 'Does previous response to clomifene citrate influence the selection of gonadotropin dosage given in subsequent superovulation treatment cycles?', Journal of Assisted Reproduction and Genetics, vol. 23, pp. 427 - 431, http://dx.doi.org/10.1007/s10815-006-9065-x

Prakash A; Li TC; Tuckerman E; Laird S; Wells M; Ledger WL, 2006, 'A study of luteal phase expression of inhibin, activin, and follistatin subunits in the endometrium of women with recurrent miscarriage', Fertility and Sterility, vol. 86, pp. 1723 - 1730, http://dx.doi.org/10.1016/j.fertnstert.2006.05.040

Ledger WL, 2006, 'Current status of research using human embryonic stem cells', Southern Medical Journal, vol. 99, pp. 1438 - 1441, http://dx.doi.org/10.1097/01.smj.0000251393.74733.3c

Ledger WL, 2006, 'Human embryonic stem cells: A justification for their use in medical therapeutics', Southern Medical Journal, vol. 99, pp. 1436 - 1437, http://dx.doi.org/10.1097/01.smj.0000251409.10054.ee

Laird SM; Tuckerman E; Prakash A; Ledger W; Li TC, 2005, 'Endometrial CD56(+) cells and implantation failure after IVF.', PLACENTA, vol. 26, pp. A26 - A26, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000231496500102&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Bahathiq AO; Stewart RL; Baxter L; Wells M; Moore HD; Ledger WL, 2005, 'Tissue immunoexpression and messenger ribonucleic acid localization of inhibin/activin subunit in human epididymis', Fertility and Sterility, vol. 83, pp. 78 - 85, http://dx.doi.org/10.1016/j.fertnstert.2004.05.104

Ola B; Ledger WL, 2005, 'Endometriosis and infertility', Women's Health Medicine, vol. 2, pp. 15 - 17, http://dx.doi.org/10.1383/wohm.2.1.15.58878

Prakash A; Laird S; Tuckerman E; Li TC; Ledger WL, 2005, 'Inhibin A and activin A may be used to predict pregnancy outcome in women with recurrent miscarriage', Fertility and Sterility, vol. 83, pp. 1758 - 1763, http://dx.doi.org/10.1016/j.fertnstert.2004.11.072

Ledger W, 2005, 'Clinical pharmacology of gonadotrophin preparations', Reproductive BioMedicine Online, vol. 10, pp. 19 - 24, http://dx.doi.org/10.1016/S1472-6483(11)60386-6

Ledger WL, 2005, 'Regulation of reproduction in the UK', Human Fertility, vol. 8, pp. 65 - 67, http://dx.doi.org/10.1080/14647270500030704

Ola B; Ledger WL, 2005, 'In vitro fertilisation', Current Obstetrics and Gynaecology, vol. 15, pp. 314 - 323, http://dx.doi.org/10.1016/j.curobgyn.2005.06.006

Ledger WL, 2005, 'Molecular basis of premature ovarian failure', Journal of the British Menopause Society, vol. 11, pp. 173, http://dx.doi.org/10.1258/136218005775544246

Out HJ; Rutherford A; Fleming R; Tay CCK; Trew G; Ledger W; Cahill D, 2004, 'A randomized, double-blind, multicentre clinical trial comparing starting doses of 150 and 200 IU of recombinant FSH in women treated with the GnRH antagonist ganirelix for assisted reproduction', Human Reproduction, vol. 19, pp. 90 - 95, http://dx.doi.org/10.1093/humrep/deh044

Jones GL; Benes K; Clark TL; Denham R; Holder MG; Haynes TJ; Mulgrew NC; Shepherd KE; Wilkinson VH; Singh M, 2004, 'The Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (PCOSQ): A validation', Human Reproduction, vol. 19, pp. 371 - 377, http://dx.doi.org/10.1093/humrep/deh048

Rostami-Hodjegan A; Lennard MS; Tucker GT; Ledger WL, 2004, 'Monitoring plasma concentrations to individualize treatment with clomiphene citrate', Fertility and Sterility, vol. 81, pp. 1187 - 1193, http://dx.doi.org/10.1016/j.fertnstert.2003.07.044

Pezeshki M; Taherian AA; Gharavy M; Ledger WL, 2004, 'Menstrual characteristics and pregnancy in women after renal transplantation', International Journal of Gynecology and Obstetrics, vol. 85, pp. 119 - 125, http://dx.doi.org/10.1016/j.ijgo.2003.09.013

Farag K; Hassan I; Ledger WL, 2004, 'Prediction of preeclampsia: Can it be achieved?', Obstetrical and Gynecological Survey, vol. 59, pp. 464 - 482, http://dx.doi.org/10.1097/00006254-200406000-00025

Ledger WL; Skull J, 2004, 'Amenorrhoea: Investigation and treatment', Current Obstetrics and Gynaecology, vol. 14, pp. 254 - 260, http://dx.doi.org/10.1016/j.curobgyn.2004.04.004

Amker SAK; Li TC; Ledger WL, 2004, 'Ovulation induction using laparoscopic ovarian drilling in women with polycystic ovarian syndrome: Predictors of success', Human Reproduction, vol. 19, pp. 1719 - 1724, http://dx.doi.org/10.1093/humrep/deh343

Refaat BA; Bahathiq AO; Sockanathan S; Stewart RL; Wells M; Ledger WL, 2004, 'Production and localization of activins and activin type IIA and IIB receptors by the human endosalpinx', Reproduction, vol. 128, pp. 249 - 255, http://dx.doi.org/10.1530/rep.1.00156

Sallam HN; Sadek SS; van Wely M; Ola B; Ledger WL, 2004, 'Ultrasound-guided embryo transfer in ART cycles increases pregnancy rate - Meta-analysis of truly randomized trials', Evidence-based Obstetrics and Gynecology, vol. 6, pp. 133 - 136, http://dx.doi.org/10.1016/j.ebobgyn.2004.07.016

Ledger WL; Ubeda A, 2004, 'Implications of an irreversible procedure [2] (multiple letters)', Fertility and Sterility, vol. 82, pp. 1473 - 1474, http://dx.doi.org/10.1016/j.fertnstert.2004.08.005

Ledger W, 2004, 'Prognostic factors of ovarian stimulation in IVF - Selecting the initial dose of gonadotrophin', Revista Iberoamericana de Fertilidad y Reproduccion Humana, vol. 21, pp. 417

Ledger W, 2004, 'Drawbacks to IVF', Revista Iberoamericana de Fertilidad y Reproduccion Humana, vol. 21, pp. 418

Ledger WL, 2003, 'Laparoscopy for investigation of pelvic pain: new approaches?', Curr Opin Obstet Gynecol, vol. 15, pp. 257 - 258, http://dx.doi.org/10.1097/01.gco.0000072861.73466.27

Amer SAK; Li TC; Ledger WL, 2003, 'Laparoscopic ovarian drilling in women with polycystic ovarian syndrome: a reappraisal of the factors affecting the clinical outcome', HUMAN REPRODUCTION, vol. 18, pp. 175 - 176, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208316000508&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lahiri S; Anobile CJ; Stewart P; Ledger WL, 2003, 'Changes in circulating concentrations of inhibins A and pro-α C during first trimester medical termination of pregnancy', Human Reproduction, vol. 18, pp. 744 - 748, http://dx.doi.org/10.1093/humrep/deg187

Reeve L; Ledger WL; Pacey AA, 2003, 'Does the Arg-Gly-Asp (RGD) adhesion sequence play a role in mediating sperm interaction with the human endosalpinx?', Human Reproduction, vol. 18, pp. 1461 - 1468, http://dx.doi.org/10.1093/humrep/deg296

Ledger WL, 2003, 'Models for future delivery of care in infertility - Hospital-based services', Human Fertility, vol. 6, http://dx.doi.org/10.1080/1464770312331369203

Cheong YC; Shelton JB; Laird SM; Li TC; Ledger WL; Cooke ID, 2003, 'Peritoneal fluid concentrations of matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and transforming growth factor-beta in women with pelvic adhesions', Fertility and Sterility, vol. 79, pp. 1168 - 1175, http://dx.doi.org/10.1016/S0015-0282(03)00079-7

Davies H; Greenfield D; Ledger W, 2003, 'Reproductive medicine in a late effects of cancer clinic', Human Fertility, vol. 6, pp. 9 - 12, http://dx.doi.org/10.1080/1464770312331368913

Ledger WL, 2003, 'Laparoscopy for investigation of pelvic pain: New approaches?', Current Opinion in Obstetrics and Gynecology, vol. 15, pp. 257 - 258, http://dx.doi.org/10.1097/00001703-200306000-00008

Ledger WL, 2003, 'Non-reproductive consequences of polycystic ovary syndrome', Current Obstetrics and Gynaecology, vol. 13, pp. 350 - 354, http://dx.doi.org/10.1016/S0957-5847(03)00072-6

Lok F; Ledger WL; Li TC, 2003, 'Surgical intervention in infertility management', Human Fertility, vol. 6, http://dx.doi.org/10.1080/1464770312331369273

Al-Azemi M; Ledger WL; Diejomaoh M; Mousa M; Makhseed M; Omu A, 2003, 'Measurement of inhibin a and inhibin pro-αC in early human pregnancy and their role in the prediction of pregnancy outcome in patients with recurrent pregnancy loss', Fertility and Sterility, vol. 80, pp. 1473 - 1479, http://dx.doi.org/10.1016/S0015-0282(03)02215-5

Bahathiq A; Wells M; Ledger W, 2002, 'Activins and follistatin may participate in sperm biology and in early embryo development', JOURNAL OF PATHOLOGY, vol. 198, pp. 19A - 19A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000177903200076&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ledger W, 2002, 'What to do about the polycystic ovary 'epidemic'', Current Opinion in Obstetrics and Gynecology, vol. 14, pp. 293 - 294, http://dx.doi.org/10.1097/00001703-200206000-00008

Ledger WL, 2002, 'In vitro fertilization', Current Obstetrics and Gynaecology, vol. 12, pp. 269 - 275, http://dx.doi.org/10.1016/S0957-5847(02)90274-X

Silverberg K; Daya S; Auray JP; Duru G; Ledger W; Wikland M; Bouzayen R; O'Brien M; Falk B; Beresniak A, 2002, 'Analysis of the cost effectiveness of recombinant versus urinary follicle-stimulating hormone in in vitro fertilization/intracytoplasmic sperm injection programs in the United States', Fertility and Sterility, vol. 77, pp. 107 - 113, http://dx.doi.org/10.1016/S0015-0282(01)02945-4

Cheong YC; Shelton JB; Laird SM; Richmond M; Kudesia G; Li TC; Ledger WL, 2002, 'IL-1, IL-6 and TNF-α concentrations in the peritoneal fluid of women with pelvic adhesions', Human Reproduction, vol. 17, pp. 69 - 75

Ledger WL, 2002, 'Patient scheduling for gonadotrophin-releasing hormone antagonist protocols', Human Fertility, vol. 5, http://dx.doi.org/10.1080/1464727992000199801

Cheong YC; Laird SM; Shelton JB; Ledger WL; Li TC; Cooke ID, 2002, 'The correlation of adhesions and peritoneal fluid cytokine concentrations: A pilot study', Human Reproduction, vol. 17, pp. 1039 - 1045

Amer SAK; Gopalan V; Li TC; Ledger WL; Cooke ID, 2002, 'Long term follow-up of patients with polycystic ovarian syndrome after laparoscopic ovarian drilling: Clinical outcome', Human Reproduction, vol. 17, pp. 2035 - 2042

Muttukrishna S; Sharma S; Barlow DH; Ledger W; Groome N; Sathanandan M, 2002, 'Serum inhibins, estradiol, progesterone and FSH in surgical menopause: A demonstration of ovarian pituitary feedback loop in women', Human Reproduction, vol. 17, pp. 2535 - 2539

Bahathiq AO; Stewart RL; Wells M; Moore HD; Pacey AA; Ledger WL, 2002, 'Production of activins by the human endosalpinx', Journal of Clinical Endocrinology and Metabolism, vol. 87, pp. 5283 - 5289, http://dx.doi.org/10.1210/jc.2001-011884

Ledger WL, 2002, 'HRT as add-back therapy', Reviews in Gynaecological Practice, vol. 2, pp. 40 - 42, http://dx.doi.org/10.1016/S1471-7697(02)00013-8

Muttukrishna S; North RA; Morris J; Schellenberg JC; Taylor RS; Asselin J; Ledger W; Groome N; Reman C, 2001, 'Serum inhibin A and activin A are elevated prior to the onset of pre eclampsia (vol 15, pg 1640, 2001)', HUMAN REPRODUCTION, vol. 16, pp. 2477 - 2477, http://dx.doi.org/10.1093/humrep/16.11.2477

Muttukrishna S; Farouk A; Sharma S; Evans L; Groome N; Ledger W; Sathanandan M, 2001, 'Serum activin A and follistatin in disorders of spermatogenesis in men', European Journal of Endocrinology, vol. 144, pp. 425 - 429, http://dx.doi.org/10.1530/eje.0.1440425

Nasseri S; Ledger WL, 2001, 'Clomiphene citrate in the twenty-first century', Human Fertility, vol. 4, pp. 145 - 151, http://dx.doi.org/10.1080/1464727012000199212

Cheong YC; Laird SM; Li TC; Shelton JB; Ledger WL; Cooke ID, 2001, 'Peritoneal healing and adhesion formation/reformation', Human Reproduction Update, vol. 7, pp. 556 - 566, http://dx.doi.org/10.1093/humupd/7.6.556

Asbóth G; Price SA; Bellinger J; Ledger W; Barlow DH; López Bernal A, 2001, 'Characterization of adenylyl cyclases in cultured human granulosa cells', Reproduction, vol. 121, pp. 217 - 228, http://dx.doi.org/10.1530/rep.0.1210217

Marcus S; Ledger W, 2001, 'Efficacy and safety of long-acting GnRH agonists in in vitro fertilization and embryo transfer', Human Fertility, vol. 4, pp. 85 - 93, http://dx.doi.org/10.1080/1464727012000199351

Ledger WL, 2001, 'Measurement of inhibin A and activin A in pregnancy - Possible diagnostic applications', Molecular and Cellular Endocrinology, vol. 180, pp. 117 - 121, http://dx.doi.org/10.1016/S0303-7207(01)00512-3

Ledger WL, 2001, 'Assisted conception: What does the future hold?', Current Opinion in Obstetrics and Gynecology, vol. 13, pp. 305 - 307, http://dx.doi.org/10.1097/00001703-200106000-00010

Muttukrishna S; North RA; Morris J; Schellenberg JC; Taylor RS; Asselin J; Ledger W; Groome N; Redman C, 2001, 'Erratum: Serum inhibin A and activin A are elevated prior to the onset of pre eclampsia (Human Reproduction)', Human Reproduction, vol. 16, pp. 2477

Daya S; Ledger W; Auray JP; Duru G; Silverberg K; Wikland M; Bouzayen R; Howles CM; Beresniak A, 2001, 'Cost-effectiveness modelling of recombinant FSH versus urinary FSH in assisted reproduction techniques in the UK', Human Reproduction, vol. 16, pp. 2563 - 2569, http://dx.doi.org/10.1093/humrep/16.12.2563

Ledger WL, 2000, 'Could tight garments cause endometriosis?', BJOG, vol. 107, pp. 705, http://dx.doi.org/10.1111/j.1471-0528.2000.tb13323.x

Muttukrishna S; Child T; Lockwood GM; Groome NP; Barlow DH; Ledger WL, 2000, 'Serum concentrations of dimeric inhibins, activin A, gonadotrophins and ovarian steroids during the menstrual cycle in older women.', Hum Reprod, vol. 15, pp. 549 - 556, http://dx.doi.org/10.1093/humrep/15.3.549

Ledger WL; Skull J, 2000, 'Rationing fertility services in the NHS: A provider's perspective', Human Fertility, vol. 3, pp. 155 - 156, http://dx.doi.org/10.1080/1464727002000198881

Flynn ME; Ledger WL, 2000, 'The pros and cons of the oral contraceptive pill', Current Obstetrics and Gynaecology, vol. 10, pp. 91 - 98, http://dx.doi.org/10.1054/cuog.2000.0121

Lenton E; Soltan A; Hewitt J; Thomson A; Davies W; Ashraf N; Sharma V; Jenner L; Ledger W; McVeigh E, 2000, 'Induction of ovulation in women undergoing assisted reproductive techniques: Recombinant human FSH (follitropin alpha) versus highly purified urinary FSH (urofollitropin HP)', Human Reproduction, vol. 15, pp. 1021 - 1027

Jackson N; Biddolph SC; Ledger W; Groome NP; Manek S, 2000, 'Inhibin expression in normal and pre-eclamptic placental tissue', International Journal of Gynecological Pathology, vol. 19, pp. 219 - 224, http://dx.doi.org/10.1097/00004347-200007000-00004

Bahatiq A; Ledger W, 2000, 'Inhibins and activins and their activity in male reproductive biology', Reproductive Medicine Review, vol. 8, pp. 87 - 106, http://dx.doi.org/10.1017/S0962279900000168

Muttukrishna S; North RA; Morris J; Schellenberg JC; Taylor RS; Asselin J; Ledger W; Groome N; Redman CWG, 2000, 'Serum inhibin A and activin A are elevated prior to the onset of pre-eclampsia', Human Reproduction, vol. 15, pp. 1640 - 1645, http://dx.doi.org/10.1093/humrep/15.7.1640

Lashen H; Ledger W; Lopez-Bernal A; Barlow D, 1999, 'Prediction of ovarian response and in-vitro fertilization outcome using age, follicle stimulating hormone (FSH), luteinizing hormone (LH), and FSH/LH ratio: a second look', HUMAN REPRODUCTION, vol. 14, pp. 104 - 104, http://dx.doi.org/10.1093/humrep/14.Suppl_3.104

Lockwood GM; Muttukrishna S; Groome NP; Ledger WL; Manek S, 1999, 'Immunohistochemical localisation of inhibin and activin subunits in normal and polycystic ovaries', JOURNAL OF PATHOLOGY, vol. 187, pp. 29A - 29A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000079173200116&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ledger WL, 1999, 'Endometriosis and infertility: An integrated approach', International Journal of Gynecology and Obstetrics, vol. 64, pp. 33 - 40

Lashen H; Ledger W; Remohi J; Pellicer A, 1999, 'Management of poor responders in IVF (multiple letters) [1]', Human Reproduction, vol. 14, pp. 1919, http://dx.doi.org/10.1093/humrep/14.7.1919

Lashen H; Ledger W; Bernai AL; Barlow D, 1999, 'Extremes of body mass do not adversely affect the outcome of superovulation and in-vitro fertilization', Human Reproduction, vol. 14, pp. 712 - 715

Lashen H; Ledger W; Lopez-Bernal A; Barlow D, 1999, 'Poor responders to ovulation induction: Is proceeding to in-vitro fertilization worthwhile?', Human Reproduction, vol. 14, pp. 964 - 969

Muttukrishna S; Chamberlain P; Evans LW; Asselin J; Groome NP; Ledger WL, 1999, 'Amniotic fluid concentrations of dimeric inhibins, activin A and follistatin in pregnancy', European Journal of Endocrinology, vol. 140, pp. 420 - 424, http://dx.doi.org/10.1530/eje.0.1400420

Lau CP; Ledger WL; Groome NP; Barlow DH; Muttukrishna S, 1999, 'Dimeric inhibins and activin A in human follicular fluid and oocyte-cumulus culture medium', Human Reproduction, vol. 14, pp. 2525 - 2530, http://dx.doi.org/10.1093/humrep/14.10.2525

Al-Azemi M; Ledger WL; Lockwood GM; Barlow DH, 1999, 'Successful transvaginal ultrasound-guided ablation of a cervical pregnancy in a patient with simultaneous intrauterine pregnancy after in vitro fertilization and embryo transfer', Human Fertility, vol. 2, pp. 67 - 69, http://dx.doi.org/10.1080/1464727992000198341

Ledger W, 1999, 'Infertility, but not fertility drug use, was a risk factor for borderline ovarian cancer in nulliparous women', Evidence-based Obstetrics and Gynecology, vol. 1, pp. 67, http://dx.doi.org/10.1054/ebog.1999.0049

Lockwood GM; Muttukrishna S; Groome NP; Matthews DR; Ledger WL, 1998, 'Mid-Follicular Phase Pulses of Inhibin B Are Absent in Polycystic Ovarian Syndrome and Are Initiated by Successful Laparoscopic Ovarian Diathermy: A Possible Mechanism Regulating Emergence of the Domi', The Journal of Clinical Endocrinology & Metabolism, vol. 83, pp. 1730 - 1735, http://dx.doi.org/10.1210/jcem.83.5.4756

Lashen H; Ledger W; López Bernal A; Evans B; Barlow D, 1998, 'Superovulation with a high gonadotropin dose for in vitro fertilization: is it effective?', J Assist Reprod Genet, vol. 15, pp. 438 - 443, http://dx.doi.org/10.1007/bf02744938

Lashen H; Ledger W, 1998, 'Effects of agonist dose on in-vitro fertilization.', Hum Reprod, vol. 13, pp. 2973 - 2974, http://dx.doi.org/10.1093/humrep/13.10.2973

Jackson N; Biddolph SC; Ledger W; Manek S, 1998, 'Inhibin expression in the normal and pre-eclamptic placental tissue', JOURNAL OF PATHOLOGY, vol. 186, pp. 26A - 26A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000075727500104&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Manek S; Charles M; Ledger W, 1998, 'Endometrial cytology revisited - A comparative study of the Tao brush (IUMC endometrial sampler) and the pipelle biopsy as diagnostic tools', JOURNAL OF PATHOLOGY, vol. 186, pp. 26A - 26A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000075727500102&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lashen H; Ledger W; Lopez-Bernal A; Barlow D, 1998, 'Total dose of gonadotrophin-releasing hormone agonist: factors affecting it and its effect on in-vitro fertilization outcome', HUMAN REPRODUCTION, vol. 13, pp. 184 - 184, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000075359300346&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lashen H; Ledger W; Lopez-Bernal A; Barlow D, 1998, 'Proceeding to IVF in patients producing four follicles or less: is it worthwhile?', HUMAN REPRODUCTION, vol. 13, pp. 51 - 52, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000075359300096&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Bagratee JS; Lockwood G; López Bernal A; Barlow DH; Ledger WL, 1998, 'Comparison of highly purified FSH (Metrodin-high purity) with pergonal for IVF superovulation', Journal of Assisted Reproduction and Genetics, vol. 15, pp. 65 - 69, http://dx.doi.org/10.1007/BF02766827

Lockwood GM; Muttukrishna S; Ledger WL, 1998, 'Inhibins and activins in human ovulation, conception and pregnancy', Human Reproduction Update, vol. 4, pp. 284 - 295, http://dx.doi.org/10.1093/humupd/4.3.284

Lashen H; Ledger W; Alvarez C; Bernabeu R, 1998, 'Effects of agonist dose on in-vitro fertilization (multiple letters) [1]', Human Reproduction, vol. 13, pp. 2973 - 2974

Lockwood GM; Ledger WL; Barlow DH; Groome NP; Muttukrishna S, 1998, 'Identification of the source of inhibins at the time of conception provides a diagnostic role for them in very early pregnancy', American Journal of Reproductive Immunology, vol. 40, pp. 303 - 308, http://dx.doi.org/10.1111/j.1600-0897.1998.tb00058.x

Lockwood GM; Muttukrishna S; Groome NP; Matthews DR; Ledger WL, 1998, 'Mid-follicular phase pulses of inhibin B are absent in polycystic ovarian syndrome and are initiated by successful laparoscopic ovarian diathermy: A possible mechanism regulating emergence of the domi', Journal of Clinical Endocrinology and Metabolism, vol. 83, pp. 1730 - 1735, http://dx.doi.org/10.1210/jcem.83.5.4756

Lockwood GM; Groome NP; Muttukrishna S; Ledger WL, 1998, 'Inhibin b levels are prognostic of the perimenopausal transition in women with reduced ovarian reserve and regular cycles', International Journal of Fertility and Menopausal Studies, vol. 43, pp. 217 - 218

Birdsall M; Ledger W; Groome N; Abdalla H; Muttukrishna S, 1997, 'Inhibin A and Activin A in the First Trimester of Human Pregnancy', The Journal of Clinical Endocrinology & Metabolism, vol. 82, pp. 1557 - 1560, http://dx.doi.org/10.1210/jcem.82.5.3934

Child TJ; Ledger WL; Barlow DH, 1997, 'Number of embryos transferred and age of mother.', Fertil Steril, vol. 68, pp. 746 - 748, https://www.ncbi.nlm.nih.gov/pubmed/9341627

Lockwood GM; Muttukrishna S; Groome NP; Ledger WL, 1997, 'Source of inhibin and activin in early pregnancy', HUMAN REPRODUCTION, vol. 12, pp. P226 - P226, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997YD97600459&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lockwood GM; Muttukrishna S; Groome NP; Ledger WL, 1997, 'Predicting the unpredictable: Inhibin B is prognostic of unexpected over and under response to gonadotrophin stimulation in IVF treatment cycles.', FERTILITY AND STERILITY, pp. O183 - O183, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XY16000182&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lockwood GM; Muttukrishna S; Ledger W; Groome N; Dolfing J; Jansen CAM, 1997, 'Optimization of non-analogue IVF: a role for inhibin B in predicting patients liable to a premature LH surge or an inadequate response', HUMAN REPRODUCTION, vol. 12, pp. P79 - P79, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997YD97600312&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Lashen H; Ledger W; Bernal A; Evans B; Barlow D, 1997, 'Superovulation with a high gonadotrophin dose for in vitro fertilization.', FERTILITY AND STERILITY, pp. O128 - O128, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XY16000127&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Child TJ; Watson NR; Ledger WL, 1997, 'Sequential bilateral adnexal torsion after a single cycle of gonadotropin ovulation induction with intrauterine insemination', Fertility and Sterility, vol. 67, pp. 573 - 575, http://dx.doi.org/10.1016/S0015-0282(97)80090-8

Lockwood GM; Ledger WL; Barlow DH; Groome NP; Muttukrishna S, 1997, 'Measurement of inhibin and activin in early human pregnancy: Demonstration of fetoplacental origin and role in prediction of early- pregnancy outcome', Biology of Reproduction, vol. 57, pp. 1490 - 1494, http://dx.doi.org/10.1095/biolreprod57.6.1490

Muttukrishna S; Knight PG; Groome NP; Redman CWG; Ledger WL, 1997, 'Activin A and inhibin A as possible endocrine markers for preeclampsia', Lancet, vol. 349, pp. 1285 - 1288, http://dx.doi.org/10.1016/S0140-6736(96)09264-1

Birdsall M; Ledger W; Groome N; Abdalla H; Muttukrishna S, 1997, 'Inhibin A and activin A in the first trimester of human pregnancy', Journal of Clinical Endocrinology and Metabolism, vol. 82, pp. 1557 - 1560, http://dx.doi.org/10.1210/jcem.82.5.3934

Muttukrishna S; Child TJ; Groome NP; Ledger WL, 1997, 'Source of circulating levels of inhibin A, pro alpha C-containing inhibins and activin A in early pregnancy', Human Reproduction, vol. 12, pp. 1089 - 1093, http://dx.doi.org/10.1093/humrep/12.5.1089

Child TJ; Ledger WL; Barlow DH; Roest J; Van Heusden AM; Verhoeff A; Mous HVH; Zeilmaker GH, 1997, 'Number of embryos transferred and age of mother [3] (multiple letters)', Fertility and Sterility, vol. 68, pp. 746 - 748

Muttukrishna S; Groome N; Ledger W, 1997, 'Gonadotropic control of secretion of dimeric inhibins and activin A by human granulosa-luteal cells in vitro', Journal of Assisted Reproduction and Genetics, vol. 14, pp. 566 - 574, http://dx.doi.org/10.1023/A:1022524516824

Lashen H; Ledger W; Davies WAR; Smith R, 1996, 'Oocyte release in luteinized unruptured follicles with a second dose of human chorionic gonadotrophin', Middle East Fertility Society Journal, vol. 1, pp. 226 - 229

Birdsall MA; Lockwood GM; Ledger WL; Johnson PM; Chamley LW, 1996, 'Antiphospholipid antibodies in women having in-vitro fertilization', Human Reproduction, vol. 11, pp. 1185 - 1189, http://dx.doi.org/10.1093/oxfordjournals.humrep.a019352

Lockwood GM; Muttukrishna S; Groome NP; Knight PG; Ledger WL, 1996, 'Circulating inhibins and activin A during GnRH-analogue down-regulation and ovarian hyperstimulation with recombinant FSH for in-vitro fertilization-embryo transfer', Clinical Endocrinology, vol. 45, pp. 741 - 748, http://dx.doi.org/10.1046/j.1365-2265.1996.8510861.x

Todd BS; Ledger WL, 1995, 'A computer-based flowcharting system for clinical protocols', Informatics for Health and Social Care, vol. 20, pp. 177 - 198, http://dx.doi.org/10.3109/14639239508995004

Mahmud G; Lopez Bernal A; Yudkin P; Ledger W; Barlow DH, 1995, 'A controlled assessment of the in vitro fertilization performance of British women of indian origin compared with white women', Fertility and Sterility, vol. 64, pp. 103 - 106

Lockwood GM; Ledger WL; Barlow DH, 1995, 'Successful pregnancy outcome in a renal transplant patient following in-vitro fertilization', Human Reproduction, vol. 10, pp. 1528 - 1530, http://dx.doi.org/10.1093/HUMREP/10.6.1528

Clark AM; Ledger W; Galletly C; Tomlinson L; Blaney F; Wang X; Norman RJ, 1995, 'Weight loss results in significant improvement in pregnancy and ovulation rates in anovulatory obese women', Human Reproduction, vol. 10, pp. 2705 - 2712, http://dx.doi.org/10.1093/oxfordjournals.humrep.a135772

Todd BS; Ledger WL, 1995, 'A computer-based flowcharting system for clinical protocols', Medical Informatics, vol. 20, pp. 177 - 198

Angell RR; Xian J; Keith J; Ledger W; Baird DT, 1994, 'First meiotic division abnormalities in human oocytes: mechanism of trisomy formation.', Cytogenet Cell Genet, vol. 65, pp. 194 - 202, http://dx.doi.org/10.1159/000133631

Ledger WL; Sweeting VM; Chatterjee S, 1994, 'Rapid diagnosis of early ectopic pregnancy in an emergency gynaecology service-are measurements of progesterone, intact and free β human chorionic gonadotrophin helpful?', Human Reproduction, vol. 9, pp. 157 - 160, http://dx.doi.org/10.1093/oxfordjournals.humrep.a138307

Wang XJ; Ledger W; Payne D; Jeffrey R; Matthews CD, 1994, 'The contribution of embryo cryopreservation to in-vitro fertilization/gamete intra-fallopian transfer: 8 years experience', Human Reproduction, vol. 9, pp. 103 - 109, http://dx.doi.org/10.1093/oxfordjournals.humrep.a138296

Witkin SS; Jeremias J; Toth M; Ledger WJ, 1993, 'Cell-mediated immune response to the recombinant 57-kDa heat-shock protein of Chlamydia trachomatis in women with salpingitis.', J Infect Dis, vol. 167, pp. 1379 - 1383, http://dx.doi.org/10.1093/infdis/167.6.1379

Angell RR; Xian J; Keith J; Ledger W; Baird DT, 1993, 'First meiotic division abnormalities in human oocytes: Mechanism of trisomy formation', Cytogenetics and Cell Genetics, vol. 65, pp. 194 - 202

Tovanabutra S; Illingworth PJ; Ledger WL; Glasier AF; Baird DT, 1993, 'The relationship between peripheral immunoactive inhibin, human chorionic gonadotrophin, oestradiol and progesterone during human pregnancy', Clinical Endocrinology, vol. 38, pp. 101 - 107, http://dx.doi.org/10.1111/j.1365-2265.1993.tb00979.x

Wu WX; Brooks J; Millar MR; Ledger WL; Glasier AF; Mcneilly AS, 1993, 'Immunolocalization of oestrogen and progesterone receptors in the human decidua in relation to prolactin production', Human Reproduction, vol. 8, pp. 1129 - 1135, http://dx.doi.org/10.1093/oxfordjournals.humrep.a138206

Ledger PW, 1992, 'Skin biological issues in electrically enhanced transdermal delivery', Advanced Drug Delivery Reviews, vol. 9, pp. 289 - 307, http://dx.doi.org/10.1016/0169-409x(92)90027-n

TOVANABUTRA S; SAUNDERS PTK; SMITH KB; LEDGER WL; MILLAR MR; PRITCHARDJONES K; DAVIDSON D; BAIRD DT, 1992, 'CELLULAR-LOCALIZATION OF INHIBIN ACTIVIN SUBUNIT MESSENGER-RNAS IN HUMAN PLACENTAL COTYLEDONS FROM EARLY AND TERM PREGNANCY', JOURNAL OF ENDOCRINOLOGY, vol. 135, pp. P100 - P100, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1992JX47500140&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ledger W; Clark A; Olesnicky G; Norman R, 1992, 'Life-threatening rupture of an interstitial ectopic pregnancy arising from oocyte donation: Failure of early detection by quantitive human chorionic gonadotropin (hCG) and progesterone estimation', Journal of Assisted Reproduction and Genetics, vol. 9, pp. 289 - 291, http://dx.doi.org/10.1007/BF01203832

Yong EL; Glasier A; Hillier H; Ledger W; Caird L; Beattie G; Sweeting V; Thong J; Baird DT, 1992, 'Effect of cyclofenil on hormonal dynamics, follicular development and cervical mucus in normal and oligomenorrhoeic women', Human Reproduction, vol. 7, pp. 39 - 43, http://dx.doi.org/10.1093/oxfordjournals.humrep.a137553

Ledger WL; Sweeting VM; Hillier H; Baird DT, 1992, 'Inhibition of ovulation by low-dose mifepristone (RU 486)', Human Reproduction, vol. 7, pp. 945 - 950, http://dx.doi.org/10.1093/oxfordjournals.humrep.a137776

Angell RR; Ledger W; Yong EL; Harkness L; Baird DT, 1991, 'Cytogenetic analysis of unfertilized human oocytes', Human Reproduction, vol. 6, pp. 568 - 573, http://dx.doi.org/10.1093/oxfordjournals.humrep.a137381

Baird DT; Ledger WL; Glasier AF, 1990, '14 Induction of ovulation-cost-effectiveness and future prospects', Bailliere's Clinical Obstetrics and Gynaecology, vol. 4, pp. 639 - 650, http://dx.doi.org/10.1016/S0950-3552(05)80315-3

Witkin SS, 1989, 'Papillomavirus Infection and an Allergic Response to Candida in Women With Recurrent Vaginitis', JAMA: The Journal of the American Medical Association, vol. 261, pp. 1584 - 1584, http://dx.doi.org/10.1001/jama.1989.03420110058023

LEDGER WL; THOMAS EJ; BROWNING D; LENTON EA; COOKE ID, 1989, 'Suppression of gonadotrophin secretion does not reverse premature ovarian failure', BJOG: An International Journal of Obstetrics & Gynaecology, vol. 96, pp. 196 - 199, http://dx.doi.org/10.1111/j.1471-0528.1989.tb01662.x

Ledger W, 1988, 'Surgical Asepsis in Labor and Delivery', Infection Control and Hospital Epidemiology, vol. 9, pp. 469 - 470, http://dx.doi.org/10.2307/30145165

Ledger WL; Anderson ABM, 1987, 'The influence of steroid hormones on the uterine cervix during pregnancy', Journal of Steroid Biochemistry, vol. 27, pp. 1029 - 1034, http://dx.doi.org/10.1016/0022-4731(87)90186-5

Ledger WL; Webster MA; Anderson ABM; Turnbull AC, 1985, 'Effect of inhibition of prostaglandin synthesis on cervical softening and uterine activity during ovine parturition resulting from progesterone withdrawal induced by epostane', Journal of Endocrinology, vol. 105, pp. 227 - 233, http://dx.doi.org/10.1677/joe.0.1050227

Ledger WL; Webster M; Harrison LP; Anderson ABM; Turnbull AC, 1985, 'Increase in cervical extensibility during labor induced after isolation of the cervix from the uterus in pregnant ewes', American Journal of Obstetrics and Gynecology, vol. 151, pp. 397 - 402, http://dx.doi.org/10.1016/0002-9378(85)90311-4

Gupta GN; Saxena BB; Landesman R; Ledger WJ, 1984, 'Subcutaneous bioabsorbable pellets of norethindrone for contraception in women: Phase I. Clinical study.', Fertil Steril, vol. 41, pp. 726 - 731, https://www.ncbi.nlm.nih.gov/pubmed/6714449

Ledger WL; Ellwood DA; Taylor MJ, 1983, 'Cervical softening in late pregnant sheep by infusion of prostaglandin E-2 into a cervical artery.', J Reprod Fertil, vol. 69, pp. 511 - 515, http://dx.doi.org/10.1530/jrf.0.0690511

Cheong YC; Hung Yu Ng E; Ledger WL, 'Acupuncture and assisted conception', , http://dx.doi.org/10.1002/14651858.cd006920

Conference Papers

Riepsamen A; Gilchrist R; Ledger W, 2019, 'Oocyte-secreted serum biomarkers and reproductive potential in women', in Oocyte-secreted serum biomarkers and reproductive potential in women, Oxford University Press, Vienna, pp. i21 - i21, presented at 35th Annual Meeting of the European Society of Human Reproduction and Embryology, Vienna, 23 - 26 June 2019, http://dx.doi.org/10.1093/humrep/34.Supplement_1.1

Ledger W; Crespi S; Hu H; Kolibianakis EM; Griesinger G, 2015, 'Decreased healthcare resource utilization among women undergoing IVF/ICSI treated with GnRH antagonist protocols as compared to GnRH agonist protocols', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Lisbon, PORTUGAL, pp. 297 - 298, presented at 31st Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Lisbon, PORTUGAL, 14 - 17 June 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000359740302080&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Riepsamen A; Listijono D; Ledger W; Wu L; Sinclair D; Homer H, 2015, 'Inhibition of sirtuin activity and impaired synthesis of the sirtuin NAD plus co-factor disrupts oocyte meiotic maturation', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Lisbon, PORTUGAL, pp. 309 - 309, presented at 31st Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Lisbon, PORTUGAL, 14 - 17 June 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000359740302106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Riepsamen A; Listijono D; Kilani S; Sweeten P; Cooke S; Ledger W; Wu L; Sinclair D; Homer H, 2015, 'Sirtuins are required for forming fertilisation-ready eggs', in BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, WILEY-BLACKWELL, pp. 40 - 40, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000356713000085&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Li Z; Wang YA; Ledger W; Edgar DH; Sullivan EA, 2014, 'Clinical outcomes following cryopreservation of blastocysts by vitrification and slow freezing: a population-based cohort study', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Munich, GERMANY, pp. 23 - 23, presented at 30th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Munich, GERMANY, 29 June - 02 July 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000359745300056&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ledger W; Jones G; Tiplady S; Duffy S; Johnson S, 2013, 'IMPACT OF DIGITAL HOME OVULATION TEST USAGE ON STRESS, PSYCHOLOGICAL WELLBEING AND QUALITY OF LIFE DURING EVALUATION OF SUBFERTILITY: A RANDOMISED CONTROLLED TRIAL.', in FERTILITY AND STERILITY, ELSEVIER SCIENCE INC, Boston, MA, pp. S411 - S411, presented at International-Federation-of-Fertility-Societies 21st World Congress on Fertility and Sterility / 69th Annual Meeting of the American-Society-for-Reproductive-Medicine, Boston, MA, 12 - 17 October 2013, http://dx.doi.org/10.1016/j.fertnstert.2013.07.624

Tamhankar V; Jones GL; Magill P; Skull JD; Ledger W, 2013, 'Investigation of the impact of emotional health on pregnancy rates after assisted conception', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, London, ENGLAND, pp. 277 - 278, presented at 29th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), London, ENGLAND, 07 - 10 July 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000320467700653&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Scholten I; Chambers GM; van Loendersloot L; van der Veen F; Repping S; Gianotten J; Hompes PGA; Ledger W; Mol BWJ, 2013, 'The impact of assisted reproductive technologies on the incidence of multiple pregnancies from a population perspective', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, London, ENGLAND, pp. 283 - 284, presented at 29th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), London, ENGLAND, 07 - 10 July 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000320467700667&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jones G; Jacques R; Radley S; Woods H; Ledger W; Alazzam M; Tidy J, 2013, 'IMPACT OF TREATMENT FOR GYNAECOLOGICAL CANCER UPON HEALTH-RELATED QUALITY OF LIFE IN ROUTINE CLINICAL PRACTICE', in INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, LIPPINCOTT WILLIAMS & WILKINS, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330379500165&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jones GL; Radley S; Dixon S; Jacques R; Brennan V; Wood H; Ledger W, 2013, 'Evaluating the impact of a 'virtual clinic' on the quality and cost of patient care in urogynaecology: an RCT', in BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, WILEY-BLACKWELL, pp. 287 - 288, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000320781601048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tiplady S; Ledger W; Godbert S; Hart S; Johnson S, 2013, 'Detection of two urinary hormones by a new home ovulation test to identify the wider fertile window: a randomised comparative laboratory study of home ovulation tests', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, London, ENGLAND, pp. 244 - 245, presented at 29th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), London, ENGLAND, 07 - 10 July 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000320467700576&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Cheong Y; Reading I; Sadek K; Ledger WL; Li TC, 2013, 'To lyse or not to lyse: results from a randomized controlled trial of adhesiolysis versus diagnostic laparoscopy in women with chronic pelvic pain', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, London, ENGLAND, pp. 76 - 76, presented at 29th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), London, ENGLAND, 07 - 10 July 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000320467700173&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Brennan VK; Dixon S; Jones G; Radley S; Jacques R; Wood H; Ledger W, 2013, 'AN ECONOMIC EVALUATION ALONGSIDE A CLINICAL TRIAL (EEACT) IN PELVIC FLOOR MEDICINE', in VALUE IN HEALTH, ELSEVIER SCIENCE INC, pp. A334 - A334, http://dx.doi.org/10.1016/j.jval.2013.08.071

Jones G; Jacques R; Thompson J; Woods H; Ledger W; Alazzam M; Radley S; Tidy J, 2013, 'IMPACT OF TRIPLE INCISION VULVECTOMY ON QUALITY OF LIFE AND PELVIC FLOOR OUTCOMES IN WOMEN WITH VULVAL CANCER', in INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, LIPPINCOTT WILLIAMS & WILKINS, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330379501196&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ledger W; Jones G; Campbell M; Tiplady S; Johnson S, 2012, 'Impact of use of home ovulation tests on the levels of stress in women trying to conceive: a randomised controlled trial', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Istanbul, TURKEY, presented at 28th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Istanbul, TURKEY, 01 - 04 July 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325299600026&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tiplady S; Johnson S; Jones G; Ledger W, 2012, 'Attitudes and opinions of women using digital home ovulation tests whilst trying to conceive', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Istanbul, TURKEY, presented at 28th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Istanbul, TURKEY, 01 - 04 July 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325299600586&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Refaat B; Simpson H; Ledger W, 2012, 'Role of activins, inducible nitric oxide synthase and mucin-1 in the regulation of human Fallopian tube and in the pathogenesis of ectopic pregnancy', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Istanbul, TURKEY, presented at 28th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Istanbul, TURKEY, 01 - 04 July 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325299600403&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Chapman MG; Kilani S; Ledger W, 2012, 'Meiotic spindle formation differs in ICSI cycles in which final oocyte maturation is stimulated by urinary or recombinant HCG', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Istanbul, TURKEY, presented at 28th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Istanbul, TURKEY, 01 - 04 July 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325299600613&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Coughlan C; Sinagra M; Ledger W; Li TC; Laird SM, 2012, 'Expression of integrins and their prognostic value in the endometrium of women with recurrent implantation failure', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Istanbul, TURKEY, presented at 28th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Istanbul, TURKEY, 01 - 04 July 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325299600544&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ledger WL, 2011, 'Avoidable loss of fertility', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Stockholm, SWEDEN, pp. I41 - I41, presented at 27th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology, Stockholm, SWEDEN, 03 - 06 July 2011, http://dx.doi.org/10.1093/humrep/26.s1.27

Gordon K; Levy MJ; Ledger W; Kolibianakis EM; IJzerman-Boon PC, 2011, 'Reducing The Incidence of Weekend Oocyte Retrievals In A rFSH/GnRH Antagonist Protocol By Optimizing The Start Day of rFSH And Delaying Human Chorionic Gonadotropin (hCG) By 1 Day', in FERTILITY AND STERILITY, ELSEVIER SCIENCE INC, Rancho Mirage, CA, pp. S16 - S16, presented at 59th Annual Meeting of the Pacific-Coast-Reproductive-Society, Rancho Mirage, CA, 13 - 17 April 2011, http://dx.doi.org/10.1016/j.fertnstert.2011.01.076

Metwally M; Ledger WL; Li TC, 2009, 'Effect of Increased Body Mass Index on the Endometrial Protein Profile in the Peri-Implantation Period in Women with Recurrent Miscarriage', in REPRODUCTIVE SCIENCES, SAGE PUBLICATIONS INC, Glasgow, SCOTLAND, pp. 192A - 192A, presented at 56th Annual Meeting of the Society-for-Gynecologic-Investigation, Glasgow, SCOTLAND, 17 - 21 March 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000263609800430&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

El Azemi N; Refaat B; Chapman N; Aplin J; Ledger W, 2009, 'The Expression of Inducible Nitric Oxide Synthetase (iNOS) and MUC1 in Human Fallopian Tube during the Menstrual Cycle and in Ectopic Pregnancy', in REPRODUCTIVE SCIENCES, SAGE PUBLICATIONS INC, Glasgow, SCOTLAND, pp. 187A - 187A, presented at 56th Annual Meeting of the Society-for-Gynecologic-Investigation, Glasgow, SCOTLAND, 17 - 21 March 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000263609800412&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Holman AJ; Irwin DE; Ledger W; Anderson P; Wiebinga CJ; Lloyd AC, 2008, 'COSTS AND OUTCOMES ASSOCIATED WITH IN VITRO FERTILISATION (IVF) OR INTRACYTOPLASMIC SPERM INJECTION (ICSI) USING RECOMBINANT FOLLICLE STIMULATING HORMONE (RFSH)', in VALUE IN HEALTH, WILEY-BLACKWELL PUBLISHING, INC, pp. A424 - A425, http://dx.doi.org/10.1016/S1098-3015(10)66434-0

Connolly M; Ledger WL, 2008, 'PRICE-ELASTICITY OF DEMAND FOR INFERTILITY SERVICES IN GERMANY', in VALUE IN HEALTH, WILEY-BLACKWELL PUBLISHING, INC, pp. A427 - A427, http://dx.doi.org/10.1016/S1098-3015(10)66442-X

Ledger WL; Wiebinga CJ; Holman AJ; Irwin DE; Lloyd AC, 2007, 'Costs and outcomes associated with use of recombinant follicle stimulating hormone (rFSH) during in vitro fertilisation (IVF) treatment in a United Kingdom centre', in VALUE IN HEALTH, BLACKWELL PUBLISHING, pp. A374 - A374, http://dx.doi.org/10.1016/S1098-3015(10)65322-3

Amer S; Ledger WL; Li TC, 2007, 'Randomized controlled trial of laparoscopic ovarian diathermy vs clomifene as first treatment of anovulatory polycystic ovarian syndrome', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Lyon, FRANCE, pp. I59 - I59, presented at 23rd Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology, Lyon, FRANCE, 01 - 04 July 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255322200140&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Metwally M; Ledger WL; Li TC, 2007, 'The effect of increased body mass index on the risk of miscarriage: a meta-analysis', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Lyon, FRANCE, pp. I85 - I86, presented at 23rd Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology, Lyon, FRANCE, 01 - 04 July 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255322200203&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Jones GL; Jenkinson C; Ledger WL; Campbell MJ; Taylor N; Kennedy S, 2007, 'Rethinking the cardinal symptoms of endometriosis and their relationship to quality of life: feeling sick, tired and pain on bowel movements', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Lyon, FRANCE, pp. I48 - I48, presented at 23rd Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology, Lyon, FRANCE, 01 - 04 July 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255322200113&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Connolly MP; Hoorens S; Gallo F; Ledger WL, 2007, 'Assessment of long-run economic benefits associated with in-vitro fertilization (IVF) funding decisions: A simplified lifetime tax calculation', in VALUE IN HEALTH, BLACKWELL PUBLISHING, pp. A238 - A239, http://dx.doi.org/10.1016/S1098-3015(10)64906-6

Ledger WL, 2007, 'Minimal ovarian stimulation', in Tan SL; Gomel V; Gosden R; Tulandi T (eds.), PROCEEDINGS OF THE 14TH WORLD CONGRESS ON IN VITRO FERTILIZATION & 3RD WORLD CONGRESS ON IN VITRO MATURATION, MEDIMOND S R L, Montreal, CANADA, pp. 373 - 378, presented at 14th World Congress on In Vitro Fertilization/3rd World Congress on In Vitro Maturation, Montreal, CANADA, 15 - 19 September 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000251729900062&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hall JM; Lashen H; Balen A; Ledger W; Jones GL, 2007, 'The impact of polycystic ovary syndrome upon the health-related quality of life of adolescents and adults - a quantitative and comparative analysis', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Lyon, FRANCE, pp. I77 - I78, presented at 23rd Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology, Lyon, FRANCE, 01 - 04 July 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255322200183&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ghobadi C; Nguyen T; Amer S; Rostami-Hodjegan A; Lennard MS; Ledger WL, 2006, 'Evaluation of an existing model for the prediction of response to clomifene citrate', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Prague, CZECH REPUBLIC, pp. I46 - I47, presented at 22nd Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology, Prague, CZECH REPUBLIC, 18 - 21 June 2006, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000238957200115&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Cheong YC; Tay P; Luk F; Gan HC; Ledger W; Li TC; Cooke ID, 2006, 'Factors associated with repeat operations in women with endometriosis - a retrospective 10 year review', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Prague, CZECH REPUBLIC, pp. I185 - I185, presented at 22nd Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology, Prague, CZECH REPUBLIC, 18 - 21 June 2006, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000238957200472&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ghobadi C; Tien NH; Amer S; Rostami-Hodjegan A; Lennard MS; Ledger WL, 2006, 'Validation of an existing model for the prediction of response to clomifene citrate', in BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, BLACKWELL PUBLISHING, Univ Coll London, London, ENGLAND, pp. 635 - 635, presented at Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Univ Coll London, London, ENGLAND, 19 - 22 December 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000237116100059&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ledger W; Gallo F; Hoorens S; Ziebe S; Connolly M, 2006, 'Present discounted value of children born using IVF compared with naturally conceived children: a simplified UK calculation', in HUMAN REPRODUCTION, OXFORD UNIV PRESS, Prague, CZECH REPUBLIC, pp. I74 - I75, presented at 22nd Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology, Prague, CZECH REPUBLIC, 18 - 21 June 2006, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000238957200183&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

McIlveen M; Cutting R; Ledger W, 2005, 'Alterations in the GnRH antagonist protocol used can improve pregnancy rates.', in FERTILITY AND STERILITY, ELSEVIER SCIENCE INC, Montreal, CANADA, pp. S40 - S40, presented at Conjoint Annual Meeting of the American-Society-for-Reproductive-Medicine/Canadian-Fertility-and-Andrology-Society, Montreal, CANADA, 15 - 19 October 2005, http://dx.doi.org/10.1016/j.fertnstert.2005.07.096

McIlveen M; Skull J; Ledger W, 2005, 'Can IVF cycle cancellation be predicted using the antral follicle count in poor responders?', in FERTILITY AND STERILITY, ELSEVIER SCIENCE INC, Montreal, CANADA, pp. S275 - S275, presented at Conjoint Annual Meeting of the American-Society-for-Reproductive-Medicine/Canadian-Fertility-and-Andrology-Society, Montreal, CANADA, 15 - 19 October 2005, http://dx.doi.org/10.1016/j.fertnstert.2005.07.715

Bahathiq AO; Kadva A; Ledger W, 2002, 'Short term fluctuation in peripheral concentrations of inhibin B in fertile men.', in FERTILITY AND STERILITY, ELSEVIER SCIENCE INC, SEATTLE, WASHINGTON, pp. S283 - S283, presented at 58th Annual Meeting of the American-Society-for-Reproductive-Medicine, SEATTLE, WASHINGTON, 12 - 17 October 2002, http://dx.doi.org/10.1016/S0015-0282(02)03953-5

Tomsu M; Pacey AA; Li TC; Ledger WL, 2002, 'Increased sperm DNA damage in partners of women with unexplained recurrent miscarriages: preliminary report.', in FERTILITY AND STERILITY, ELSEVIER SCIENCE INC, SEATTLE, WASHINGTON, pp. S166 - S166, presented at 58th Annual Meeting of the American-Society-for-Reproductive-Medicine, SEATTLE, WASHINGTON, 12 - 17 October 2002, http://dx.doi.org/10.1016/S0015-0282(02)03834-7

Ledger W; Schlaff W; Olive D, 1999, 'Endometriosis: A mystery tour for the clinician and patient', in BenRafael Z; Shoham Z (eds.), FIRST WORLD CONGRESS ON CONTROVERSIES IN OBSTETRICS, GYNECOLOGY & INFERTILITY, MEDIMOND S R L, PRAGUE, CZECH REPUBLIC, pp. 179 - 181, presented at 1st Congress on Controversies in Obstetrics, Gynecology and Infertility, PRAGUE, CZECH REPUBLIC, 28 - 31 October 1999, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000088383900050&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Posters

Scholten I; Chambers GM; van Loendersloot L; van der Veen F; Repping S; Gianotten J; Ledger W; Mol BWJ, 2013, 'Towards Understanding the impact of assisted reproductive technologies on the incidence of multiple pregnancies from a population perspective. European Society of Human Reproduction and Embryology (ES'

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Professor William Ledger

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